[构棘根的化学成分研究]

[Studies on chemical constituents from roots of Cudrania cochinchinensis].

作者信息

Wang Ying-Hong, Feng Zi-Ming, Jiang Jian-Shang, Zhang Pei-Cheng

机构信息

Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2007 Mar;32(5):406-9.

PMID:17511146

Abstract

OBJECTIVE

To study the chemical constituents from the roots of Cudrania cochinchinensis.

METHOD

The chemical constituents of C. cochinchinensis were isolated and purified by silica gel, polyamide column chromatography, Their structures were identified on the basis of spectroscopic data.

RESULT

Six compounds were isolated and identified. Their structures were established as 3, 5, 7, 4"-tetrahydroxyflavanone-7-O-(6"-acetyl)-glucoside (1), 3, 5, 7, 4'-tetra hydroxyflavanone-7-O-glucoside (2), 2', 4', 5, 7-tetrahydroxy-6-prenyldihydroflavanone (3), 5, 7, 4'-trihysdroxy-6-prenylisoflavanone (4), 1, 3, 5, 6-tetrahydroxyxanthone (5), stilbene-2, 4, 3', 5'-tetraol (6).

CONCLUSION

Compound 1 was isolated from this genus, while compounds 4 and 5 were isolated from this plant for the first time.

摘要

目的

研究葎草的根的化学成分。

方法

采用硅胶柱色谱、聚酰胺柱色谱对葎草的化学成分进行分离纯化，并根据光谱数据鉴定其结构。

结果

分离鉴定出6个化合物，分别为3,5,7,4”-四羟基黄酮-7-O-(6”-乙酰基)-葡萄糖苷（1）、3,5,7,4'-四羟基黄酮-7-O-葡萄糖苷（2）、2',4',5,7-四羟基-6-异戊烯基二氢黄酮（3）、5,7,4'-三羟基-6-异戊烯基异黄酮（4）、1,3,5,6-四羟基呫吨酮（5）、二苯乙烯-2,4,3',5'-四醇（6）。