Sun Xialing, Ren Jihao, Lu Yongde, Yin Tuanfang, Wu Weijing, Tang Yueying, Hu Binya
Department of Otolaryngology, the Second Hospital of Xiangya Medical College, Central South University, Changsha, 410011, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007 Feb;21(4):146-8.
To investigate the efficacy of round window catheter placement with dexamethasone perfusion for 13 patients with intractable sudden sensorineural hearing loss (SSNHL).
Dexamethasone (2.5 mg) was perfused transtympanically through round window catheter by Micro-infusion pump. The perfusion was taken twice a day and continued for an hour each time, for a total of 7 days.
Thirteen patients have been followed up for 1 month. Five of them (38.5%) were demonstrated a 17-54 dB improvement in pure-tone threshold average (PTA). The other 8 patients (61.5%) had no effect.
Round window catheter placement with dexamethasone perfusion is a cost-effective and useful treatment for SSNHL patients who had no effect through conventional therapy, although hearing thresholds of these patients had hardly improved to normal levels.
探讨圆窗置管并灌注地塞米松对13例难治性突发性感音神经性听力损失（SSNHL）患者的疗效。
通过微量输液泵经圆窗导管经鼓膜向鼓室内灌注地塞米松（2.5毫克）。每天灌注2次，每次持续1小时，共7天。
13例患者随访1个月。其中5例（38.5%）纯音听阈均值（PTA）提高了17 - 54分贝。另外8例（61.5%）无效。
对于经传统治疗无效的SSNHL患者，圆窗置管并灌注地塞米松是一种经济有效的治疗方法，尽管这些患者的听力阈值几乎未恢复到正常水平。
