[巴西亚马逊地区的皮肤黏膜利什曼病]
[Mucocutaneous leishmaniasis in Brazilian Amazonia].
作者信息
Camuset G, Remy V, Hansmann Y, Christmann D, Gomes de Albuquerque C, Sena Casseb G-A
机构信息
Service des maladies infectieuses et tropicales, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, 67000 Strasbourg, France.
出版信息
Med Mal Infect. 2007 Jun;37(6):343-6. doi: 10.1016/j.medmal.2007.03.012. Epub 2007 May 23.
BACKGROUND
This study had for aim to describe the clinical aspects and favoring factors of mucosal Leishmaniasis in an Amazonian population of 30,000 habitants in Guajara-Mirim (Rondonia-Brazil).
MATERIAL AND METHOD
A descriptive study was made of 16 patients with mucosal Leishmaniasis among 170 patients infected by Leishmania. Inclusion criteria were a mucosal lesion and positivity of direct microscopic examination. The patients were investigated retrospectively.
RESULTS
Patients with mucosal Leishmaniasis were young and mostly male The absence of treatment and the number of cutaneous lesions were probably responsible for the mucosal form, as well as the host immune response and maybe, the parasite species or vector characteristics.
CONCLUSION
The mucosal form of leishmaniasis affects more often young male patients and this form must be detected early to avoid destructing lesions.
背景
本研究旨在描述瓜亚拉-米林（巴西朗多尼亚州）一个拥有3万居民的亚马逊人群中黏膜利什曼病的临床特征及相关影响因素。
材料与方法
对170例利什曼原虫感染者中的16例黏膜利什曼病患者进行了描述性研究。纳入标准为存在黏膜病变且直接显微镜检查呈阳性。对患者进行回顾性调查。
结果
黏膜利什曼病患者多为年轻男性。未接受治疗以及皮肤病变数量可能是导致黏膜型疾病的原因，此外还有宿主免疫反应，也可能与寄生虫种类或传播媒介特征有关。
结论
利什曼病的黏膜型更常影响年轻男性患者，必须尽早发现这种类型以避免出现破坏性病变。
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