Eisenhauer T, Müller U, Schuff-Werner P, Armstrong V W, Bosch T, Thiery J, Gurland H, Seidel D
Department of Nephrology, University Hospital Göttingen, Germany.
ASAIO Trans. 1991 Jul-Sep;37(3):M494-6.
Simultaneous heparin extracorporeal LDL precipitation (HELP)-dialysis was carried out at weekly intervals in six patients with end-stage renal failure, associated hyperlipidemia, and a high risk of premature atherosclerosis. Evaluating 135 single treatments, a mean acute total cholesterol/LDL reduction of 31% and 39%, respectively, was found, while clearance of urinary substances was comparable to that in regular hemodialysis treatment. Treatment tolerance was excellent and no derangements in albumin, hemodialysis parameters, or blood coagulation were detected.
对6例终末期肾衰竭、伴有高脂血症且有过早发生动脉粥样硬化高风险的患者，每隔一周进行一次肝素体外低密度脂蛋白沉淀（HELP）-透析。评估135次单次治疗发现，急性总胆固醇/低密度脂蛋白平均分别降低31%和39%，而尿物质清除率与常规血液透析治疗相当。治疗耐受性良好，未检测到白蛋白、血液透析参数或血液凝固方面的紊乱。
