Blanco Carlos, Harford Thomas C, Nunes Edward, Grant Bridget, Hasin Deborah
Department of Psychiatry, New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, United States.
Drug Alcohol Depend. 2007 Nov 2;91(1):91-6. doi: 10.1016/j.drugalcdep.2007.04.003. Epub 2007 May 18.
To better understand the underlying concepts of substance dependence and abuse, the present study examines the factor structure of DSM-IV lifetime criteria for cannabis and cocaine use disorders. Data for this study were drawn from the National Longitudinal Alcohol Epidemiologic Survey (NLAES), a large nationally representative U.S. sample aged 18 years and older. Exploratory factor analysis (EFA) examined the factor structure for each substance and the factors were related to background covariates using latent variable modeling techniques. Separate analyses were conducted for lifetime marijuana and cocaine users. A two-factor solution was identified for each substance and was similar to DSM-IV abuse and dependence. The factors were highly correlated for both cannabis (r=0.73) and cocaine (r=0.77). Background variables accounted only for a modest amount of factor variance. In conjunction with the findings in alcohol use disorders, these results support the use of consistent criteria across substances in DSM-IV and ICD-10, and suggest that the consistent finding of two correlated factors across substances needs to be better understood.
为了更好地理解物质依赖和滥用的潜在概念，本研究考察了《精神疾病诊断与统计手册》第四版（DSM-IV）中大麻和可卡因使用障碍终生标准的因素结构。本研究的数据取自全国酒精流行病学纵向调查（NLAES），这是一个具有全国代表性的美国样本，年龄在18岁及以上。探索性因素分析（EFA）考察了每种物质的因素结构，并使用潜在变量建模技术将这些因素与背景协变量相关联。对终生使用大麻和可卡因的人群分别进行了分析。每种物质都确定了一个双因素解决方案，且与DSM-IV中的滥用和依赖情况相似。大麻（r = 0.73）和可卡因（r = 0.77）的这两个因素高度相关。背景变量仅占因素方差的适度比例。结合酒精使用障碍的研究结果，这些结果支持在DSM-IV和ICD-10中对不同物质使用一致的标准，并表明需要更好地理解不同物质中两个相关因素的一致发现。
