Camann W R, Hortvet L A, Hughes N, Bader A M, Datta S
Department of Anaesthesia, Brigham and Women's Hospital, Boston, Massachusetts 02115.
Br J Anaesth. 1991 Nov;67(5):565-8. doi: 10.1093/bja/67.5.565.
We have studied the effect of analgesia on maternal temperature (oral and tympanic membrane) progression in 53 women during normal spontaneous labour. Three groups were studied: two received extradural analgesia with a continuous infusion of 0.25% bupivacaine with or without the addition of fentanyl; the third group received only parenteral opioid analgesia. All patients were afebrile and without clinical evidence of infection at the beginning of the study. Both groups of patients receiving extradural analgesia had a consistent and significant increase in temperature after approximately 5 h of analgesia; no such trend was observed in the parenteral opioid group. Alterations in mechanisms of heat dissipation may explain these findings.
我们研究了镇痛对53名正常自然分娩妇女母体体温（口腔和鼓膜温度）变化的影响。研究分为三组：两组接受硬膜外镇痛，持续输注0.25%布比卡因，其中一组添加芬太尼，另一组未添加；第三组仅接受胃肠外阿片类镇痛。所有患者在研究开始时均无发热，也无感染的临床证据。接受硬膜外镇痛的两组患者在镇痛约5小时后体温均持续且显著升高；胃肠外阿片类药物组未观察到这种趋势。散热机制的改变可能解释了这些发现。
