Brown S, Kurtsikashvili G, Alonso-Echanove J, Ghadua M, Ahmeteli L, Bochoidze T, Shushtakashvili M, Eremin S, Tsertsvadze E, Imnadze P, O'Rourke E
Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
J Hosp Infect. 2007 Jun;66(2):160-6. doi: 10.1016/j.jhin.2007.03.007. Epub 2007 May 21.
Surgical site infections (SSIs) are a serious problem worldwide. Little is known about the epidemiology of SSI in the former Soviet Union. In order to determine the prevalence and predictors of SSI in the Republic of Georgia, we undertook a multicentre observational study of SSIs in three urban hospitals in the capital, Tbilisi. Point prevalence studies (PPS) were performed every 3-5 weeks from September 2000 to January 2002 using the National Nosocomial Infections Surveillance (NNIS) System definitions. All patients who had undergone surgery and were present in participating departments at study hospitals on the day of PPS were included. Of 872 surgical procedures, 146 (16.7%) were complicated by SSI. The prevalence of SSI varied by procedure and risk category. On multivariate regression analysis, age, wound class, one hospital (B) and urological surgery were predictive of SSI. In a separate model, NNIS risk index was highly predictive of SSI. Antibiotic prophylaxis was rare (29.5% of operations), while postoperative antibiotic use was common. SSI is an important problem in the Republic of Georgia. Potential areas for intervention include antibiotic prophylaxis and shaving practices for skin preparation.
手术部位感染(SSIs)在全球范围内都是一个严重的问题。对于前苏联地区手术部位感染的流行病学情况,人们了解甚少。为了确定格鲁吉亚共和国手术部位感染的患病率及其预测因素,我们在首都第比利斯的三家城市医院开展了一项关于手术部位感染的多中心观察性研究。从2000年9月至2002年1月,每3至5周采用国家医院感染监测(NNIS)系统的定义进行一次现患率研究(PPS)。所有接受过手术且在现患率研究当天在参与研究的医院相关科室住院的患者均被纳入。在872例手术中,有146例(16.7%)发生了手术部位感染并发症。手术部位感染的患病率因手术类型和风险类别而异。多因素回归分析显示,年龄、伤口类别、一家医院(B)以及泌尿外科手术是手术部位感染的预测因素。在另一个模型中,NNIS风险指数对手术部位感染具有高度预测性。预防性使用抗生素的情况很少见(占手术的29.5%),而术后使用抗生素则较为普遍。手术部位感染在格鲁吉亚共和国是一个重要问题。潜在的干预领域包括预防性使用抗生素以及皮肤准备时的备皮方法。