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心血管手术后医院感染的评估。

Evaluation of nosocomial infections following cardiovascular surgery.

作者信息

Coşkun Diler, Aytaç Jale

机构信息

Department of Microbiology, Medical Faculty, Istanbul Science University, Istanbul, Turkey.

出版信息

Anadolu Kardiyol Derg. 2007 Jun;7(2):164-8.

Abstract

OBJECTIVE

To evaluate nosocomial infections (NI) following cardiovascular surgery (CVS), and to share the first seven-year experience of the infection control commission in a private medical center.

METHODS

Active prospective and laboratory based surveillance program of the hospital from January 1999 to December 2005 was used and all patients who were found to have NIs after CVS during their stay or readmission were included.

RESULTS

A total of 14,502 cardiovascular operations were performed and 416 (2.9%) patients had 494 NIs. The most prevalent infections were surgical site infections (42%) and urinary tract infections (22%). The most frequently isolated microorganisms were coagulase-negative staphylococci (19%), Escherichia coli (16%) and Staphylococcus aureus (16%). A total of 99 patients (24%) died. The mortality rates were high in patients with blood-stream infections (58%) and lower respiratory tract infections (37%). The 2003 was the year with the lowest NI rate when compared to 2000, 2001, 2002, 2004, and 2005 (p< 0.005).

CONCLUSION

This study allowed an evaluation of NIs, including incidence and distribution, following CVS. While carrying on the studies to prevent NIs that are responsible for serious morbidity and mortality, risk factors also need to be identified in order to take preventive measures, other than the ones present.

摘要

目的

评估心血管手术后的医院感染(NI)情况,并分享一家私立医疗中心感染控制委员会的首个七年经验。

方法

采用1999年1月至2005年12月该医院基于实验室的主动前瞻性监测项目,纳入所有在心血管手术后住院期间或再次入院时被发现有医院感染的患者。

结果

共进行了14502例心血管手术,416例(2.9%)患者发生了494例医院感染。最常见的感染是手术部位感染(42%)和尿路感染(22%)。最常分离出的微生物是凝固酶阴性葡萄球菌(19%)、大肠杆菌(16%)和金黄色葡萄球菌(16%)。共有99例患者(24%)死亡。血流感染患者(58%)和下呼吸道感染患者(37%)的死亡率较高。与2000年、2001年、2002年、2004年和2005年相比,2003年的医院感染率最低(p<0.005)。

结论

本研究对心血管手术后的医院感染进行了评估,包括发病率和分布情况。在继续开展预防导致严重发病和死亡的医院感染的研究时,还需要确定危险因素,以便采取除现有措施之外的预防措施。

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