Wassef Medhat R, Michaels Emil I, Rangel Jeffrey M, Tsyrlin Arkadiy T
Department of Anesthesiology, Mount Sinai School of Medicine, Elmhurst Hospital, New York, USA.
Anesth Analg. 2007 Jun;104(6):1594-6, table of contents. doi: 10.1213/01.ane.0000261510.37489.00.
In this prospective, randomized, double-blind study, we evaluated whether a very low dose of spinal bupivacaine could be sufficient for safe performance of short perianal surgery.
Eighty patients were randomly assigned to receive hyperbaric bupivacaine doses of either 1.5 mg (n = 40) or 6.0 mg (n = 40).
The lower dose produced satisfactory anesthesia with a more limited block (median S4; P < 0.01), earlier time to ambulation (98 vs 147 min; P < 0.01), and hospital discharge (126 vs 249 min; P < 0.01), compared with the higher spinal dose.
The use of 1.5 mg spinal bupivacaine can be successful for short perianal surgery.
在这项前瞻性、随机、双盲研究中,我们评估了极低剂量的脊髓布比卡因是否足以安全地进行短时间肛周手术。
80例患者被随机分配接受1.5毫克(n = 40)或6.0毫克(n = 40)的高压布比卡因剂量。
与较高的脊髓剂量相比,较低剂量产生了令人满意的麻醉效果,阻滞范围更有限(中位S4;P < 0.01),下床活动时间更早(98分钟对147分钟;P < 0.01),出院时间更早(126分钟对249分钟;P < 0.01)。
使用1.5毫克脊髓布比卡因可成功用于短时间肛周手术。