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腹腔镜胃旁路术后常规上消化道造影的效用

The utility of routine postoperative upper GI series following laparoscopic gastric bypass.

作者信息

Doraiswamy Asok, Rasmussen Jason J, Pierce Jonathan, Fuller William, Ali Mohamed R

机构信息

Department of Surgery, University of California, Davis, Sacramento, CA 95817, USA.

出版信息

Surg Endosc. 2007 Dec;21(12):2159-62. doi: 10.1007/s00464-007-9314-9. Epub 2007 May 19.

Abstract

BACKGROUND

Routine upper gastrointestinal (UGI) studies following laparoscopic Roux-en-Y gastric bypass (LRYGBP) have the potential advantage of early identification of anastomotic complications. The aim of our study was to evaluate the efficacy of routine postoperative UGI and its relationship to clinical outcomes.

METHODS

Over a three-year period, 516 patients underwent LRYGBP followed by routine postoperative UGI studies. Data were collected on the results of the UGI, clinical parameters, and patient outcomes. Study groups were composed of patients with a normal UGI (Group I, n = 455), abnormal UGI not requiring further intervention (Group II, n = 36), and abnormal UGI requiring further intervention (Group III, n =25). Statistical significance was set at alpha= 0.05 level for all analyses.

RESULTS

The three study groups were not statistically different in mean age (42 years) or body mass index (BMI) (45) and were predominantly female (90%). Most patients had an uneventful postoperative course. Anastomotic complications (gastrojejunostomy and jejunojejunostomy) were uncommon (1.3%). The sensitivity of the UGI for anastomotic leak in this study was low (33%). However, all patients with alimentary limb obstruction (n = 3) had UGI evidence of this complication. Of the 516 UGI reports, there were only 25 (4.8%, Group III) that were abnormal and required some form of intervention ranging from serial imaging (84%) to reoperation (16%). Of the various clinical parameters examined, the patients in Group III demonstrated a significantly higher prevalence of fever (p < 0.001), tachycardia (p < 0.01), vomiting (p < 0.001), and postoperative day 1 leukocytosis (p < 0.005).

CONCLUSIONS

Our data suggest that routine UGI after LRYGBP has limited utility as it may result in unnecessary intervention based on false-positive results or a delay in treatment based on false-negative results. We advocate selective UGI imaging following LRYGBP based on the patient's clinical factors, particularly fever and tachycardia.

摘要

背景

腹腔镜Roux-en-Y胃旁路术(LRYGBP)后进行常规上消化道(UGI)检查具有早期发现吻合口并发症的潜在优势。我们研究的目的是评估术后常规UGI检查的有效性及其与临床结局的关系。

方法

在三年期间,516例患者接受了LRYGBP手术,随后进行了术后常规UGI检查。收集了UGI检查结果、临床参数和患者结局的数据。研究组由UGI检查结果正常的患者(I组,n = 455)、UGI检查异常但无需进一步干预的患者(II组,n = 36)和UGI检查异常需要进一步干预的患者(III组,n = 25)组成。所有分析的统计学显著性设定为α = 0.05水平。

结果

三个研究组在平均年龄(42岁)或体重指数(BMI)(45)方面无统计学差异,且大多数为女性(90%)。大多数患者术后术后病程恢复顺利。吻合口并发症(胃空肠吻合口和空肠空肠吻合口)并不常见(1.3%)。本研究中UGI对吻合口漏的敏感性较低(33%)。然而,所有患有消化道肢体梗阻的患者(n = 3)UGI检查均显示有此并发症。在516份UGI报告中,只有25份(4.8%,III组)异常,需要某种形式的干预,从系列影像学检查(84%)到再次手术(16%)。在检查的各种临床参数中,III组患者发热(p < 0.001)、心动过速(p < 0.01)、呕吐(p < 0.001)和术后第1天白细胞增多(p < 0.005)的发生率显著更高。

结论

我们的数据表明,LRYGBP术后常规UGI检查的作用有限,因为它可能因假阳性结果导致不必要的干预,或因假阴性结果导致治疗延迟。我们主张根据患者的临床因素,特别是发热和心动过速,对LRYGBP术后进行选择性UGI成像检查。

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