Department of Surgery, University of Minnesota, 520 Delaware Street SE, Minneapolis, MN 55455, USA.
J Am Coll Surg. 2012 Feb;214(2):208-13. doi: 10.1016/j.jamcollsurg.2011.10.021.
There are myriad symptoms and signs of gastrojejunal leak; prompt recognition is essential. Many surgeons use clinical predictors to guide selective use of upper gastrointestinal imaging (UGI). The appropriate practice remains undefined.
A review of patients who underwent primary laparoscopic Roux-en-Y gastric bypass between January 2002 and December 2008 was conducted. All underwent routine UGI studies on postoperative day 1. Actual gastrojejunal leak within 7 days of surgery (actual leak [AL], radiologic leaks), operative reports, patient charts, and postoperative vital signs were retrospectively reviewed.
There were 2,099 operations. Eight ALs (0.43%) occurred without associated mortality. UGI was positive in 7 AL patients and falsely positive in 6 patients. The AL patients underwent laparoscopy on postoperative days 1 and 3 (n = 5 and n = 1, respectively), laparotomy on postoperative day 3 (n = 1), and peritoneal drainage (n = 1). False-positive UGIs prompted laparoscopy (n = 3) and close observation (n = 3). Pulse was 100 to 120 beats per minute in 2 patients and fever (>38.5°C) was present in 0 AL patients. AL patients had osteogenesis imperfecta (n = 1), macronodular cirrhosis (n = 1), positive bubble test (n = 3), and concomitant splenectomy (n = 1). No jejunojejunostomy leaks were identified.
Routine UGI after laparoscopic Roux-en-Y gastric bypass has greater sensitivity than clinical signs for detecting gastrojejunal leak. Delay in the diagnosis of leakage can impact mortality, and this suggests that indications for routine UGI might still exist. Tachycardia is not a reliable early marker of leak. There might be risk factors for leak in addition to vital signs, including patient medical history or intraoperative events, which should prompt routine UGI on postoperative day 1.
胃空肠吻合口漏有多种症状和体征;及时识别至关重要。许多外科医生使用临床预测因素来指导选择性使用上消化道成像(UGI)。适当的做法仍未定义。
对 2002 年 1 月至 2008 年 12 月期间行腹腔镜 Roux-en-Y 胃旁路术的患者进行了回顾性研究。所有患者术后第 1 天行常规 UGI 检查。回顾性分析手术 7 天内的实际胃空肠吻合口漏(实际漏[AL],放射性漏)、手术报告、患者病历和术后生命体征。
共 2099 例手术。8 例(0.43%)发生吻合口漏,无相关死亡。7 例 AL 患者 UGI 阳性,6 例假阳性。AL 患者分别于术后第 1 天和第 3 天行腹腔镜检查(n=5 和 n=1),术后第 3 天行剖腹探查(n=1),行腹腔引流(n=1)。假阳性 UGI 行腹腔镜检查(n=3)和密切观察(n=3)。2 例脉搏为 100-120 次/分,0 例 AL 患者发热(>38.5°C)。AL 患者分别有骨发育不全(n=1)、大结节性肝硬化(n=1)、阳性气泡试验(n=3)和同时行脾切除术(n=1)。未发现空肠空肠吻合口漏。
腹腔镜 Roux-en-Y 胃旁路术后常规 UGI 的敏感性高于临床体征,可用于检测胃空肠吻合口漏。漏诊时间延迟会影响死亡率,这表明常规 UGI 的适应证可能仍然存在。心动过速不是漏诊的可靠早期标志物。除生命体征外,可能还有其他漏诊的危险因素,包括患者病史或术中事件,这应提示术后第 1 天常规行 UGI。