Diz Angel P, Skibinski David O F
School of Medicine, University of Swansea, Singleton Park, Swansea, UK.
Proteomics. 2007 Jun;7(12):2111-20. doi: 10.1002/pmic.200600954.
Protein expression patterns were compared in mussels from a hybrid zone between the two species Mytilus edulis and M. galloprovincialis using 2-DE. Significant differences in expression pattern were observed between species and between mussels within species. Hybrid mussels had more variable protein expression patterns than mussels of each species. This could be due to segregation at expression modifier loci in the hybrids. It is proposed that unusual hybrid expression patterns might contribute to postzygotic isolation, if such patterns reduce fitness. The use of proteomic data for testing evolutionary models, as in many transcriptomics studies, is explored with results consistent with the expectations of neutral theory.
利用双向电泳技术比较了贻贝属物种紫贻贝和地中海贻贝杂交区域的贻贝的蛋白质表达模式。在不同物种之间以及同一物种内的贻贝之间观察到了表达模式的显著差异。杂交贻贝的蛋白质表达模式比每个物种的贻贝更具变异性。这可能是由于杂交种中表达修饰位点的分离所致。有人提出，如果这种模式降低了适应性，异常的杂交表达模式可能有助于合子后隔离。如同许多转录组学研究一样，探讨了利用蛋白质组学数据来检验进化模型，结果与中性理论的预期一致。
