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眼部肌炎作为人类免疫缺陷病毒(HIV-1)感染的首发症状及其对大剂量皮质类固醇治疗的反应。

Ocular myositis as first presenting symptom of human immunodeficiency virus (HIV-1) infection and its response to high-dose cortisone treatment.

作者信息

Fabricius E M, Hoegl I, Pfaeffl W

机构信息

Department of Ophthalmology, Harlaching Hospital, München, Germany.

出版信息

Br J Ophthalmol. 1991 Nov;75(11):696-7. doi: 10.1136/bjo.75.11.696.

Abstract

A 30-year-old male presented with signs of ocular inflammation and motility disturbances in an early stage of HIV infection. The provisional diagnosis of an ocular myositis was confirmed by orbital echograms. A general check up revealed positive anti-smooth-muscle antibodies and antinuclear antibodies as well as a raised erythrocyte sedimentation rate. Oral steroid treatment in addition to steroid eyedrops achieved complete resolution of clinical and sonographic symptoms within 15 weeks. Autoimmune phenomena are well known presentations of HIV infection. In this case oral cortisone proved to be an effective therapy even in the setting of an HIV infection.

摘要

一名30岁男性在HIV感染早期出现眼部炎症和眼球运动障碍体征。眼眶超声检查确诊为眼肌炎。全面检查发现抗平滑肌抗体和抗核抗体呈阳性,红细胞沉降率升高。除了使用类固醇眼药水外,口服类固醇治疗使临床和超声症状在15周内完全缓解。自身免疫现象是HIV感染的常见表现。在这种情况下,口服可的松被证明即使在HIV感染的情况下也是一种有效的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b42/1042534/29ad2c3809c7/brjopthal00573-0058-a.jpg

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本文引用的文献

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Polymyositis associated with AIDS retrovirus.
JAMA. 1986 Nov 7;256(17):2381-3.
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