我们终于准备好对发热性中性粒细胞减少症进行门诊管理了吗？ - Suppr

Are we finally ready for outpatient management of febrile neutropenia?

作者信息

Saini Shermini, Rosoff Philip M

机构信息

Department of Pediatrics, Division of Hematology and Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

Pediatr Blood Cancer. 2007 Nov;49(6):765-6. doi: 10.1002/pbc.21224.

DOI:10.1002/pbc.21224

PMID:17514730

Abstract

摘要

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Are we finally ready for outpatient management of febrile neutropenia?我们终于准备好对发热性中性粒细胞减少症进行门诊管理了吗？

Pediatr Blood Cancer. 2007 Nov;49(6):765-6. doi: 10.1002/pbc.21224.

Early hospital discharge versus continued hospitalization in febrile pediatric cancer patients with prolonged neutropenia: A randomized, prospective study.发热性长期中性粒细胞减少的儿科癌症患者早期出院与继续住院治疗的比较：一项随机前瞻性研究。

Pediatr Blood Cancer. 2007 Nov;49(6):786-92. doi: 10.1002/pbc.21179.

A prospective, controlled, randomized, non-blind, comparative study of the efficacy and safety of a once daily high dose of ceftriaxone plus ciprofloxacin versus thrice daily ceftazidime plus amikacin in empirical therapy for febrile neutropenic patients.一项前瞻性、对照、随机、非盲、比较性研究，旨在对比每日一次大剂量头孢曲松加环丙沙星与每日三次头孢他啶加阿米卡星在发热性中性粒细胞减少患者经验性治疗中的疗效和安全性。

Eur J Intern Med. 2008 Dec;19(8):619-24. doi: 10.1016/j.ejim.2007.08.011. Epub 2008 Apr 29.

Randomized controlled trial comparing oral amoxicillin-clavulanate and ofloxacin with intravenous ceftriaxone and amikacin as outpatient therapy in pediatric low-risk febrile neutropenia.比较口服阿莫西林-克拉维酸与氧氟沙星和静脉注射头孢曲松与阿米卡星作为小儿低危发热性中性粒细胞减少症门诊治疗方案的随机对照试验。

J Pediatr Hematol Oncol. 2009 Sep;31(9):635-41. doi: 10.1097/MPH.0b013e3181acd8cd.

Single-daily ceftriaxone plus amikacin versus thrice-daily ceftazidime plus amikacin as empirical treatment of febrile neutropenia in children with cancer.单剂量头孢曲松联合阿米卡星与每日三次头孢他啶联合阿米卡星作为癌症患儿发热性中性粒细胞减少症的经验性治疗

J Paediatr Child Health. 2001 Feb;37(1):38-43. doi: 10.1046/j.1440-1754.2001.00585.x.

Once daily ceftriaxone plus amikacin vs. three times daily ceftazidime plus amikacin for treatment of febrile neutropenic children with cancer. Writing Committee for the International Collaboration on Antimicrobial Treatment of Febrile Neutropenia in Children.每日一次头孢曲松联合阿米卡星与每日三次头孢他啶联合阿米卡星治疗儿童癌症发热性中性粒细胞减少症。儿童发热性中性粒细胞减少症抗菌治疗国际协作写作委员会

Pediatr Infect Dis J. 1997 Apr;16(4):346-53. doi: 10.1097/00006454-199704000-00003.

Current approaches for risk stratification of infectious complications in pediatric oncology.

Pediatr Blood Cancer. 2007 Nov;49(6):767-73. doi: 10.1002/pbc.21205.

Early hospital discharge followed by outpatient management versus continued hospitalization of children with cancer, fever, and neutropenia at low risk for invasive bacterial infection.侵袭性细菌感染低风险的癌症、发热和中性粒细胞减少症患儿早期出院后门诊管理与持续住院治疗的比较。

J Clin Oncol. 2004 Sep 15;22(18):3784-9. doi: 10.1200/JCO.2004.01.078.

Cefepime monotherapy is as effective as ceftriaxone plus amikacin in pediatric patients with cancer and high-risk febrile neutropenia in a randomized comparison.在一项随机对照研究中，对于患有癌症且有高危发热性中性粒细胞减少症的儿科患者，头孢吡肟单药治疗与头孢曲松加阿米卡星治疗的效果相当。

J Microbiol Immunol Infect. 2009 Apr;42(2):141-7.

Cost-effectiveness of ceftriaxone and amikacin as single daily dose for the empirical management of febrile granulocytopenic children with cancer.头孢曲松和阿米卡星每日单次给药用于癌症发热性粒细胞减少症患儿经验性治疗的成本效益分析

Chemotherapy. 1997 Sep-Oct;43(5):358-66. doi: 10.1159/000239590.

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Are we finally ready for outpatient management of febrile neutropenia?

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