Stevens-Simon C, Stewart J, Nakashima I I, White M
Department of Pediatrics, University of Colorado Health Science Center, Denver, Colorado.
J Adolesc Health. 1991 Jul;12(5):403-5. doi: 10.1016/0197-0070(91)90056-r.
Fibrous dysplasia is a metabolic skeletal disorder in which the medullary spaces of affected bones are replaced by fibro-osseous tissue. Patients with fibrous dysplasia usually become symptomatic during childhood; the adolescent patient we describe is unusual because she was not known to suffer from fibrous dysplasia until she became pregnant and experienced a dramatic reactivation of the symptoms. The therapeutic implication of this case and reproductive counselling for young women with fibrous dysplasia are discussed.
纤维性发育不良是一种代谢性骨骼疾病，其中受影响骨骼的髓腔被纤维骨组织所取代。纤维性发育不良患者通常在儿童期出现症状；我们所描述的这位青少年患者很不寻常，因为直到她怀孕并经历症状的急剧复发，才被发现患有纤维性发育不良。本文讨论了该病例的治疗意义以及对患有纤维性发育不良的年轻女性的生殖咨询。
