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主动脉弓动脉瘤的杂交修复术。

Hybrid repair of aortic arch aneurysm.

作者信息

Saleh H M

机构信息

Ain Shams University Hospitals, Cairo, Egypt.

出版信息

Acta Chir Belg. 2007 Mar-Apr;107(2):173-80.

Abstract

BACKGROUND

Conventional surgical repair of the aortic arch using cardiopulmonary bypass and deep hypothermic circulatory arrest still carries a substantial rate of mortality and morbidity especially myocardial injury, and predicts a high incidence of permanent neurological injury. Endovascular stent-graft placement has been developed as an effective treatment modality in various diseases of the descending aorta. Technological improvements nowadays allow deployment in the distal arch in most instances. However, in case of total involvement of the aortic arch endovascular SG repair, the challenge is to maintain blood flow to the brain and upper extremities, that may require covering one or more aortic branches in order to establish a secure proximal landing zone, and to ensure complete exclusion of the lesion. The aim of this study is to report our ongoing experience with endovascular treatment of aortic arch aneurysms.

METHODS

During two years, 16 patients were treated with thoracic stent-grafts, after aortic arch debranching for repair of aortic arch aneurysm. All patients were at high risk for open repair and not candidates for standard endovascular repair due to inadequate proximal landing zones. Device design and implant strategy were on the basis of evaluation of aortic morphology with spiral CT. Stent grafts were inserted to repair the arch after supra-aortic vessel transposition was performed. Follow-up was 100% complete (mean 18 +/- 2.5 months, range 12-24 months). Follow-up included clinical examination, chest X-ray and computed tomography at discharge, 6 months after stent-graft placement and yearly thereafter.

RESULTS

Primary technical success rate was 100%. Patency of all endografts and conventional bypasses was 100%. No endoleak or graft migration was observed. There were no neurological complications. Surgical conversion was never required.

CONCLUSION

Hybrid aortic arch repair is technically challenging but feasible. This novel approach may be an alternative to standard open procedures in high-risk patients and emergency cases. However, the promising early results need to be confirmed by longer follow-up and larger series.

摘要

背景

使用体外循环和深低温停循环对主动脉弓进行传统手术修复,仍然具有较高的死亡率和发病率,尤其是心肌损伤,并预示着永久性神经损伤的高发生率。血管内支架移植物置入术已发展成为降主动脉各种疾病的一种有效治疗方式。如今的技术改进使得在大多数情况下能够在主动脉弓远端进行置入。然而,在主动脉弓完全受累的血管内支架移植物修复病例中,挑战在于维持脑部和上肢的血流,这可能需要覆盖一个或多个主动脉分支以建立安全的近端锚定区,并确保病变完全被隔绝。本研究的目的是报告我们对主动脉弓动脉瘤进行血管内治疗的持续经验。

方法

在两年时间里,16例患者在主动脉弓去分支后接受了胸段支架移植物治疗,以修复主动脉弓动脉瘤。所有患者进行开放修复的风险都很高,并且由于近端锚定区不足而不适合进行标准的血管内修复。根据螺旋CT对主动脉形态的评估来设计器械和植入策略。在进行主动脉弓上血管转位后插入支架移植物以修复主动脉弓。随访率为100%(平均18±2.5个月,范围12 - 24个月)。随访包括临床检查、出院时的胸部X线和计算机断层扫描、支架移植物置入后6个月以及此后每年一次。

结果

主要技术成功率为100%。所有腔内移植物和传统旁路的通畅率均为100%。未观察到内漏或移植物移位情况。没有神经并发症。从未需要进行手术转换。

结论

杂交主动脉弓修复在技术上具有挑战性,但可行。这种新方法可能是高危患者和急诊病例中标准开放手术的一种替代方法。然而,这些有前景的早期结果需要通过更长时间的随访和更大规模的系列研究来证实。

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