肾动脉的导航门控磁共振血管造影：一种肾动脉狭窄的潜在筛查工具。
Navigator-gated MR angiography of the renal arteries: a potential screening tool for renal artery stenosis.
作者信息
Maki Jeffrey H, Wilson Gregory J, Eubank William B, Glickerman David J, Millan Juan A, Hoogeveen Romhild M
机构信息
Department of Radiology (S113), University of Washington, Puget Sound VA Health Care System, 1660 S Colombian Way, Seattle, WA 98108, USA.
出版信息
AJR Am J Roentgenol. 2007 Jun;188(6):W540-6. doi: 10.2214/AJR.06.1138.
OBJECTIVE
The purpose of our study was to determine how well unenhanced navigator-gated steady-state free precession (Nav SSFP) MR angiography (MRA) performs as a screening test for the detection of renal artery stenosis.
SUBJECTS AND METHODS
Forty patients referred to rule out renal artery stenosis were imaged using an optimized Nav SSFP MRA sequence before conventional contrast-enhanced MRA (CE-MRA). Two radiologists evaluated Nav SSFP for maximum stenosis measurement, and comparison was made with CE-MRA results.
RESULTS
Fifteen of the 40 patients had greater than 50% renal artery stenosis as determined on CE-MRA. Sensitivity for detecting renal artery stenosis with Nav SSFP was 100%; specificity, 84%; negative predictive value, 100%; and positive predictive value, 79%. The average mean stenosis difference between Nav SSFP and CE-MRA was 10% +/- 9%.
CONCLUSION
Sensitivity and negative predictive value for the detection of renal artery stenosis using Nav SSFP were perfect, with an acceptable specificity of 84%. This suggests Nav SSFP is a promising technique for simple unenhanced screening for the detection of renal artery stenosis.
目的
本研究的目的是确定非增强导航门控稳态自由进动（Nav SSFP）磁共振血管造影（MRA）作为检测肾动脉狭窄的筛查试验的效果如何。
对象与方法
40例因排除肾动脉狭窄而转诊的患者在进行传统对比增强MRA（CE-MRA）之前，使用优化的Nav SSFP MRA序列进行成像。两名放射科医生评估Nav SSFP以测量最大狭窄程度，并与CE-MRA结果进行比较。
结果
在CE-MRA检查中，40例患者中有15例肾动脉狭窄超过50%。Nav SSFP检测肾动脉狭窄的敏感性为100%；特异性为84%；阴性预测值为100%；阳性预测值为79%。Nav SSFP与CE-MRA之间的平均狭窄差异为10%±9%。
结论
使用Nav SSFP检测肾动脉狭窄的敏感性和阴性预测值极佳，特异性为84%，可以接受。这表明Nav SSFP是一种有前景的技术，可用于简单的非增强筛查以检测肾动脉狭窄。
Zotero 插件