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[儿童沙门氏菌肠胃炎的临床与微生物学特征]

[Clinical and microbiological features of Salmonella gastroenteritis in children].

作者信息

Saporito Laura, Colomba Claudia, Scarlata Francesco, Li Vecchi Vatentina, Mammina Caterina, Titone Lucina

机构信息

Istituto di Patologia Infettiva e Virologia, Università di Palermo, Italy.

出版信息

Infez Med. 2007 Mar;15(1):24-9.

Abstract

The aim of our study was to evaluate the role of Salmonella spp in children hospitalised for acute gastroenteritis, and to study clinical and microbiological features of paediatric salmonellosis in our geographical area. In all, 540 patients admitted from March to September 2003 with symptoms of acute enteritis to the Infectious Diseases department of the "G. Di Cristina" hospital in Palermo were enrolled. Stool samples were collected within 48 hours of admission and tested for intestinal pathogens (bacterial, viral, parasites). Salmonella spp was detected in 18.5% of samples. The median age of infected children was 4.5 years. Salmonella enteritidis (49%) and Salmonella typhimurium (37%) were the most commonly identified genotypes. S. enteritidis infection was more frequently characterized by vomiting (65.3%) and dehydration (61.2%). Bloody diarrhoea was more common in S. typhimurium infection (40.5%). All strains were susceptible to ceftriaxone, while 40% of strains were resistant to tetracyclines and 37% to ampicillin.

摘要

我们研究的目的是评估沙门氏菌属在因急性胃肠炎住院儿童中的作用,并研究我们所在地理区域小儿沙门氏菌病的临床和微生物学特征。2003年3月至9月期间,“G. 迪克里斯蒂娜”医院巴勒莫传染病科收治的540例有急性肠炎症状的患者被纳入研究。入院48小时内采集粪便样本,检测肠道病原体(细菌、病毒、寄生虫)。18.5%的样本中检测到沙门氏菌属。感染儿童的中位年龄为4.5岁。肠炎沙门氏菌(49%)和鼠伤寒沙门氏菌(37%)是最常见的基因型。肠炎沙门氏菌感染更常见的症状是呕吐(65.3%)和脱水(61.2%)。血性腹泻在鼠伤寒沙门氏菌感染中更为常见(40.5%)。所有菌株对头孢曲松敏感,而40%的菌株对四环素耐药,37%对氨苄西林耐药。

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