Lee W S, Puthucheary S D, Boey C C
Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.
J Paediatr Child Health. 1998 Aug;34(4):387-90. doi: 10.1046/j.1440-1754.1998.00247.x.
To study the clinical features of non-typhoid Salmonella gastroenteritis and the incidence, risk factors and outcome of invasive complications in urban Malaysian children. To describe the serotypes of Salmonella species isolated and the pattern of antibiotic susceptibility.
Retrospective review of a group of 131 children with non-typhoid Salmonella gastroenteritis seen at the University Hospital, Kuala Lumpur, Malaysia from January 1994 to December 1996.
Sixty-seven percent were infants below one year of age. Fever and vomiting were seen in nearly half of children. Seven children (5.3%) had invasive complications: 5 bacteraemia and 2 meningitis. Age below 6 months, fever > 38.0 degrees C, and dehydration on admission were significantly associated with invasive complications. The commonest serotypes isolated were S. enteritidis, S. paratyphi B, and S. bovis-morbificans. A total of 94-100% of isolates were susceptible to commonly prescribed antibiotics.
Children with Salmonella gastroenteritis below 6 months of age who are febrile and dehydrated should be treated empirically with antibiotics until the result of blood culture is available.
研究马来西亚城市儿童非伤寒沙门氏菌胃肠炎的临床特征、侵袭性并发症的发生率、危险因素及转归。描述分离出的沙门氏菌血清型及抗生素敏感性模式。
回顾性分析1994年1月至1996年12月在马来西亚吉隆坡大学医院就诊的131例非伤寒沙门氏菌胃肠炎患儿。
67%为1岁以下婴儿。近半数患儿有发热和呕吐症状。7例患儿（5.3%）发生侵袭性并发症：5例菌血症和2例脑膜炎。6个月以下年龄、发热>38.0℃及入院时脱水与侵袭性并发症显著相关。最常分离出的血清型为肠炎沙门氏菌、副伤寒乙沙门氏菌和牛肠炎沙门氏菌。共94% - 100%的分离株对常用抗生素敏感。
6个月以下患沙门氏菌胃肠炎且发热、脱水的儿童，在血培养结果出来之前应经验性使用抗生素治疗。
