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Immunoprophylaxis failure against vertical transmission of hepatitis B virus: what is the mechanism and do other factors also play a role?

作者信息

Shin Jae Il, Namgung Ran, Park Min Soo, Park Kook In, Lee Chul

出版信息

Eur J Pediatr. 2008 Apr;167(4):489-90. doi: 10.1007/s00431-007-0499-7. Epub 2007 May 22.

DOI:10.1007/s00431-007-0499-7
PMID:17516085
Abstract
摘要

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Management of chronic hepatitis B in pregnancy.妊娠合并慢性乙型肝炎的管理。
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本文引用的文献

1
Effect of hepatitis B immunisation in newborn infants of mothers positive for hepatitis B surface antigen: systematic review and meta-analysis.乙肝表面抗原阳性母亲的新生儿接种乙肝疫苗的效果：系统评价与荟萃分析
BMJ. 2006 Feb 11;332(7537):328-36. doi: 10.1136/bmj.38719.435833.7C. Epub 2006 Jan 27.
2
Quantitative analysis of HBV DNA level and HBeAg titer in hepatitis B surface antigen positive mothers and their babies: HBeAg passage through the placenta and the rate of decay in babies.乙肝表面抗原阳性母亲及其婴儿的乙肝病毒DNA水平和HBeAg滴度的定量分析：HBeAg通过胎盘的情况及婴儿体内的衰减率
J Med Virol. 2003 Nov;71(3):360-6. doi: 10.1002/jmv.10493.
3
Failed postnatal immunoprophylaxis for hepatitis B: characteristics of maternal hepatitis B virus as risk factors.
乙型肝炎产后免疫预防失败：作为风险因素的母亲乙型肝炎病毒特征
Clin Infect Dis. 1998 Jul;27(1):100-6. doi: 10.1086/514610.
4
Surface gene mutants of hepatitis B virus in infants who develop acute or chronic infections despite immunoprophylaxis.尽管进行了免疫预防仍发生急性或慢性感染的婴儿中乙型肝炎病毒的表面基因变异体
Hepatology. 1997 Sep;26(3):786-91. doi: 10.1002/hep.510260336.
5
The role of transplacental hepatitis B core antibody in the mother-to-infant transmission of hepatitis B virus.经胎盘乙肝核心抗体在乙肝病毒母婴传播中的作用。
J Hepatol. 1996 Jun;24(6):674-9. doi: 10.1016/s0168-8278(96)80262-5.