Demina N S, Lysenko S V
Nauchnye Doki Vyss Shkoly Biol Nauki. 1991(9):136-53.
The literary and experimental data obtained by the authors concerning the ability of various microorganisms to synthesize exoproteases lysing the thrombi of human blood are presented in the article. Various methods of enhancing the thrombolytic activity of microorganisms cultures, the properties of some isolated and purified preparations, methods of enlarging the specificity of the enzymes to fibrin and of reduction of their toxicity are considered.
本文介绍了作者获得的有关各种微生物合成溶解人血血栓的外切蛋白酶能力的文献和实验数据。文中还探讨了提高微生物培养物溶栓活性的各种方法、一些分离和纯化制剂的特性、扩大酶对纤维蛋白的特异性以及降低其毒性的方法。
