Frauscher Birgit, Gschliesser Viola, Brandauer Elisabeth, Ulmer Hanno, Peralta Cecilia M, Müller Jörg, Poewe Werner, Högl Birgit
Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.
Department of Statistics, Informatics and Health Economics, Innsbruck Medical University, Innsbruck, Austria.
Mov Disord. 2007 Jul 30;22(10):1464-1470. doi: 10.1002/mds.21561.
In REM sleep behavior disorder (RBD), several studies focused on electromyographic characterization of motor activity, whereas video analysis has remained more general. The aim of this study was to undertake a detailed and systematic video analysis. Nine polysomnographic records from 5 Parkinson patients with RBD were analyzed and compared with sex- and age-matched controls. Each motor event in the video during REM sleep was classified according to duration, type of movement, and topographical distribution. In RBD, a mean of 54 +/- 23.2 events/10 minutes of REM sleep (total 1392) were identified and visually analyzed. Seventy-five percent of all motor events lasted <2 seconds. Of these events, 1,155 (83.0%) were classified as elementary, 188 (13.5%) as complex behaviors, 50 (3.6%) as violent, and 146 (10.5%) as vocalizations. In the control group, 3.6 +/- 2.3 events/10 minutes (total 264) of predominantly elementary simple character (n = 240, 90.9%) were identified. Number and types of motor events differed significantly between patients and controls (P < 0.05). This study shows a very high number and great variety of motor events during REM sleep in symptomatic RBD. However, most motor events are minor, and violent episodes represent only a small fraction.
在快速眼动睡眠行为障碍（RBD）中，多项研究聚焦于运动活动的肌电图特征，而视频分析则较为笼统。本研究的目的是进行详细而系统的视频分析。分析了5例患有RBD的帕金森病患者的9份多导睡眠图记录，并与性别和年龄匹配的对照组进行比较。根据持续时间、运动类型和地形分布对快速眼动睡眠期间视频中的每个运动事件进行分类。在RBD中，平均每10分钟快速眼动睡眠有54±23.2个事件（共1392个）被识别并进行视觉分析。所有运动事件的75%持续时间<2秒。在这些事件中，1155个（83.0%）被分类为基本事件，188个（13.5%）为复杂行为，50个（3.6%）为暴力行为，146个（10.5%）为发声。在对照组中，每10分钟识别出3.6±2.3个事件（共264个），主要为基本简单特征（n = 240，90.9%）。患者和对照组之间运动事件的数量和类型存在显著差异（P < 0.05）。本研究表明，有症状的RBD患者在快速眼动睡眠期间存在大量且种类繁多的运动事件。然而，大多数运动事件较为轻微，暴力发作仅占一小部分。
