Padayatchi Nesri, Friedland Gerald
Expert Opin Pharmacother. 2007 Jun;8(8):1035-7. doi: 10.1517/14656566.8.8.1035.
Global increases in multi-drug-resistant and extensively drug-resistant tuberculosis (TB), are threatening both TB and HIV treatment programs worldwide. Together, they raise concerns of a global epidemic of untreatable TB. In the developing world, the directly observed treatment, short course (DOTS) strategy is proving ineffective as available resources are being outstripped by the large number of patients needing treatment. Thus, TB treatment and outcomes are sub-optimal, and multi-drug resistant and extensively drug-resistant TB are on the rise.
全球耐多药和广泛耐药结核病的增加，正威胁着全球的结核病和艾滋病治疗项目。这两者共同引发了对无法治疗的结核病全球流行的担忧。在发展中世界，由于需要治疗的大量患者超出了现有资源，直接观察短程治疗（DOTS）策略正被证明无效。因此，结核病治疗及治疗效果并不理想，耐多药和广泛耐药结核病正在增加。
