Green K M J, Julyan P J, Hastings D L, Ramsden R T
Department of Otolaryngology, Manchester Royal Infirmary Manchester, UK.
J Laryngol Otol. 2008 Mar;122(3):238-45. doi: 10.1017/S0022215107008043. Epub 2007 May 22.
Cochlear implantation is generally accepted as a successful means of restoring auditory sensation to profoundly deaf individuals. Although most patients can expect a satisfactory outcome following implantation, some have poor speech perception outcomes. This investigation used [18F]-fluorodeoxyglucose positron emission tomography to measure cortical activity resulting from auditory stimulation in seven 'good' and four 'poor' cochlear implant recipients. Activations were significantly greater in both the primary and association cortices in the good compared with the poor implant users. We suggest that the ability to access the more specialised speech processing abilities of the auditory association cortices helps determine outcome following cochlear implantation.
人工耳蜗植入通常被认为是一种成功的手段，可为极重度聋人恢复听觉。虽然大多数患者在植入后有望获得满意的结果，但有些患者的言语感知结果较差。本研究使用[18F] - 氟脱氧葡萄糖正电子发射断层扫描技术，测量了7名“良好”和4名“较差”人工耳蜗植入受者在听觉刺激下产生的皮质活动。与植入效果较差的使用者相比，植入效果良好者的初级和联合皮质中的激活明显更强。我们认为，能够利用听觉联合皮质中更专门的言语处理能力有助于确定人工耳蜗植入后的效果。
