Moug Susan J, Horgan Paul G
University Department of Surgery, Glasgow Royal Infirmary, Queen Elizabeth Building, Alexandra Parade, Glasgow G31 2ER, UK.
Surg Oncol. 2007 Jul;16(1):53-8. doi: 10.1016/j.suronc.2007.04.005. Epub 2007 May 22.
Twenty-five percent of colorectal cancer patients present with synchronous disease in the bowel and liver. Traditionally, the primary cancer was resected and the patient re-staged some 3-4 months later. In the interim, the majority of oncology centres offered these patients chemotherapy. At re-staging, if conditions remained favourable, hepatic resection was considered. This treatment protocol was supported by the literature published in the 1990s. However, there have been many advances in aggressive multimodality care of patients with metastatic colorectal cancer and there are increasing reports of the benefits of synchronous resection for this population of patients.
25%的结直肠癌患者在肠道和肝脏同时出现病变。传统上，先切除原发性癌症，约3 - 4个月后对患者重新进行分期。在此期间，大多数肿瘤中心会为这些患者提供化疗。重新分期时，如果条件仍然有利，则考虑进行肝切除。20世纪90年代发表的文献支持了这种治疗方案。然而，在转移性结直肠癌患者的积极多模式治疗方面已经取得了许多进展，并且越来越多的报告表明同步切除对这类患者有益。
