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三种用于评估急性营养不良患病率的LQAS设计的现场试验。

A field test of three LQAS designs to assess the prevalence of acute malnutrition.

作者信息

Deitchler Megan, Valadez Joseph J, Egge Kari, Fernandez Soledad, Hennigan Mary

机构信息

Academy for Educational Development, FANTA Project, Washington DC 20009, USA.

出版信息

Int J Epidemiol. 2007 Aug;36(4):858-64. doi: 10.1093/ije/dym092. Epub 2007 May 21.

Abstract

BACKGROUND

The conventional method for assessing the prevalence of Global Acute Malnutrition (GAM) in emergency settings is the 30 x 30 cluster-survey. This study describes alternative approaches: three Lot Quality Assurance Sampling (LQAS) designs to assess GAM. The LQAS designs were field-tested and their results compared with those from a 30 x 30 cluster-survey.

METHODS

Computer simulations confirmed that small clusters instead of a simple random sample could be used for LQAS assessments of GAM. Three LQAS designs were developed (33 x 6, 67 x 3, Sequential design) to assess GAM thresholds of 10, 15 and 20%. The designs were field-tested simultaneously with a 30 x 30 cluster-survey in Siraro, Ethiopia during June 2003. Using a nested study design, anthropometric, morbidity and vaccination data were collected on all children 6-59 months in sampled households. Hypothesis tests about GAM thresholds were conducted for each LQAS design. Point estimates were obtained for the 30 x 30 cluster-survey and the 33 x 6 and 67 x 3 LQAS designs.

RESULTS

Hypothesis tests showed GAM as <10% for the 33 x 6 design and GAM as > or =10% for the 67 x 3 and Sequential designs. Point estimates for the 33 x 6 and 67 x 3 designs were similar to those of the 30 x 30 cluster-survey for GAM (6.7%, CI = 3.2-10.2%; 8.2%, CI = 4.3-12.1%, 7.4%, CI = 4.8-9.9%) and all other indicators. The CIs for the LQAS designs were only slightly wider than the CIs for the 30 x 30 cluster-survey; yet the LQAS designs required substantially less time to administer.

CONCLUSIONS

The LQAS designs provide statistically appropriate alternatives to the more time-consuming 30 x 30 cluster-survey. However, additional field-testing is needed using independent samples rather than a nested study design.

摘要

背景

在紧急情况下评估全球急性营养不良(GAM)患病率的传统方法是30×30整群抽样调查。本研究描述了替代方法:三种用于评估GAM的批量质量保证抽样(LQAS)设计。对LQAS设计进行了现场测试,并将其结果与30×30整群抽样调查的结果进行了比较。

方法

计算机模拟证实,小整群而非简单随机样本可用于GAM的LQAS评估。开发了三种LQAS设计(33×6、67×3、序贯设计)以评估10%、15%和20%的GAM阈值。2003年6月,在埃塞俄比亚的西拉罗,这些设计与30×30整群抽样调查同时进行了现场测试。采用嵌套研究设计,收集了抽样家庭中所有6至59个月儿童的人体测量、发病率和疫苗接种数据。对每种LQAS设计进行了关于GAM阈值的假设检验。获得了30×30整群抽样调查以及33×6和67×3 LQAS设计的点估计值。

结果

假设检验表明,33×6设计的GAM<10%,67×3和序贯设计的GAM≥10%。33×6和67×3设计的GAM点估计值(6.7%,CI = 3.2 - 10.2%;8.2%,CI = 4.3 - 12.1%,7.4%,CI = 4.8 - 9.9%)以及所有其他指标与30×30整群抽样调查的相似。LQAS设计的置信区间仅比30×30整群抽样调查的略宽;然而,LQAS设计所需的实施时间要少得多。

结论

LQAS设计为耗时更长的30×30整群抽样调查提供了统计学上合适的替代方法。然而,需要使用独立样本而非嵌套研究设计进行额外的现场测试。

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