Melato M, Mucli E, Poldrugo F, Valente M, Zanconati F, Okuda K
Istituto di Anatomia Patologica, Università di Trieste, Italy.
Ital J Gastroenterol. 1991 May;23(4):211-4.
A positive association between alcohol consumption and stroke incidence has been clearly established. The present study evaluated the frequency of stroke in a sample of 500 autopsied patients affected by liver cirrhosis mainly due to chronic alcohol abuse as confirmed by the histologic pattern mostly of mixed and micronodular types. Frequency of stroke was compared to that of 4,741 non-cirrhotic patients autopsied in the same period. Our findings demonstrate that stroke frequency, especially when due to thromboembolism, decreased significantly in cirrhotics. Therefore, hepatopathy is a crucial event in alcoholic patients. Nevertheless the concomitant presence of liver cirrhosis, in studies dealing with this subject, is not being currently evaluated.
饮酒与中风发病率之间的正相关关系已得到明确证实。本研究评估了500例主要因慢性酒精滥用导致肝硬化的尸检患者样本中的中风发生率，组织学模式大多为混合性和小结节型，证实了这一点。将中风发生率与同期尸检的4741例非肝硬化患者的发生率进行了比较。我们的研究结果表明，肝硬化患者的中风发生率，尤其是由血栓栓塞引起的中风发生率显著降低。因此，肝病在酒精性患者中是一个关键事件。然而，在处理这一主题的研究中，目前尚未评估肝硬化的并存情况。
