Figueiral M H, Azul A, Pinto E, Fonseca P A, Branco F M, Scully C
Faculty of Dentistry, Porto University, Guifões, Portugal.
J Oral Rehabil. 2007 Jun;34(6):448-55. doi: 10.1111/j.1365-2842.2007.01709.x.
The aim of this study was to identify and characterize aetiological and predisposing factors in denture-related stomatitis (DRS), by means of a case-control, transversal study, in a large cohort of 140 persons wearing removable maxillary polymethylamethacrylate prostheses. Data were obtained by (1) a questionnaire that included the identification of the subject, demographic and social data, medical history and behaviour; (2) intra-oral examination; (3) evaluation of the prosthesis; (4) microbiological examination; (5) yeast identification and analyses using Epi-info and the chi-square test. Results showed significant associations between DRS and yeasts, gender, age and alcohol consumption. We also found a significant relationship between the presence of yeasts and hyposalivation and decreased salivary pH. We found a highly significant difference between groups with and without DRS concerning the presence or absence of yeasts, regardless of the sample origin. Most cases of DRS showed the presence of Candida albicans. The results confirm a highly significant difference between groups with and without DRS concerning the presence or absence of yeasts.
本研究旨在通过一项病例对照横向研究，在一个由140名佩戴上颌可摘式聚甲基丙烯酸甲酯假牙的人群组成的大型队列中，识别并描述与义齿性口炎（DRS）相关的病因和诱发因素。数据通过以下方式获得：（1）一份问卷，包括受试者识别、人口统计学和社会数据、病史及行为；（2）口腔内检查；（3）假牙评估；（4）微生物学检查；（5）使用Epi-info软件和卡方检验进行酵母菌鉴定和分析。结果显示，DRS与酵母菌、性别、年龄及饮酒之间存在显著关联。我们还发现酵母菌的存在与唾液分泌减少及唾液pH值降低之间存在显著关系。无论样本来源如何，有DRS组和无DRS组在酵母菌的有无方面存在高度显著差异。大多数DRS病例显示白色念珠菌的存在。结果证实，有DRS组和无DRS组在酵母菌的有无方面存在高度显著差异。
