Wolf Eric J, Wessel Matthew M, Hirsch Marc D, Leib Martin L
The Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Ophthalmic Plast Reconstr Surg. 2007 May-Jun;23(3):242-3. doi: 10.1097/IOP.0b013e31803ecf11.
A 90-year-old man reported a 1-year history of tearing and irritation in the left eye. Ophthalmic examination was significant for bloody mucopurulent material expressed from the left nasolacrimal duct. The patient underwent external dacryocystorhinostomy with excision of a soft-tissue mass. Initial histopathologic examination of the specimen revealed an atypical lymphoid infiltrate. Subsequent immunohistochemistry suggested that the mass was reactive lymphoid hyperplasia. Lymphoid hyperplasia should be considered in the differential diagnosis of bloody epiphora, in addition to primary malignancy of the nasolacrimal duct, hematologic abnormalities, coagulopathies, vascular tumors, and giant papillary conjunctivitis.
一名90岁男性报告左眼有1年流泪和刺激感病史。眼科检查发现从左鼻泪管挤出血性黏液脓性物质。该患者接受了外路泪囊鼻腔吻合术并切除了一个软组织肿块。标本的初步组织病理学检查显示非典型淋巴细胞浸润。随后的免疫组化提示该肿块为反应性淋巴组织增生。除鼻泪管原发性恶性肿瘤、血液系统异常、凝血障碍、血管肿瘤和巨大乳头性结膜炎外，血性溢泪的鉴别诊断中应考虑淋巴组织增生。
