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无线胶囊内镜的研发与应用

The development and application of wireless capsule endoscopy.

作者信息

Glukhovsky A, Jacob H

机构信息

Alfred Mann Foundation, Santa Clarita, California, USA.

出版信息

Int J Med Robot. 2004 Jun;1(1):114-23. doi: 10.1002/rcs.13.

DOI:10.1002/rcs.13
PMID:17520603
Abstract

The introduction of the Video Capsule Endoscope (VCE) by Given Imaging Ltd. (Yoqneam, Israel) in 2001, and its subsequent approval by the FDA as a first line tool in the detection of abnormalities of the small bowel, is indicative of the rapid acceptance of capsule endoscopy by the practicing gastroenterological community. An extensive clinical trials program consistently revealed a high diagnostic yield of the VCE when compared to other diagnostic modalities of the small intestine. The capsule endoscope contains a miniature color video camera, illumination sources, lens, transmitter/controller, antenna, and a power source. It is small enough to easily swallow (11 x 26 mm), and it is propelled through the gastrointestinal (GI) tract by peristalsis. Its development was enabled by a series of technological breakthroughs that occurred at the close of the 20th century. The VCE is one of the most exciting examples of the recent trend for minimally invasive autonomous medical tools in diagnostic, monitoring, and therapeutic applications. Expanding applications of the VCE to additional parts of the GI tract, adding physiological sensors, and--in the more remote future--addition of therapeutic capabilities will likely occur as this new branch of endoscopy develops.

摘要

2001年,以色列约纳姆的Given Imaging Ltd.公司推出了视频胶囊内镜(VCE),随后它被美国食品药品监督管理局(FDA)批准为检测小肠异常的一线工具,这表明胶囊内镜已迅速被胃肠病学临床界所接受。与小肠的其他诊断方式相比,一项广泛的临床试验计划始终显示VCE具有较高的诊断率。胶囊内镜包含一个微型彩色摄像机、照明源、镜头、发射机/控制器、天线和一个电源。它小到可以轻松吞咽(11×26毫米),并通过蠕动在胃肠道中推进。它的发展得益于20世纪末出现的一系列技术突破。VCE是微创自主医疗工具在诊断、监测和治疗应用中最新趋势的最令人兴奋的例子之一。随着这一内镜新分支的发展,VCE在胃肠道其他部位的应用可能会不断扩大,增加生理传感器,并且在更遥远的未来可能会增加治疗功能。

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