Department of Gastroenterology, Rambam Healthcare Campus, Rappoport School of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.
Curr Opin Gastroenterol. 2010 Mar;26(2):129-33. doi: 10.1097/MOG.0b013e328334df17.
It is now over 8 years since small bowel capsule endoscopy (SBCE) was first introduced to the gastrointestinal community. The original capsule (Given Imaging, YoKneam, Israel) - a disposable 26 x 11 mm video capsule containing its own optical dome, light source, batteries, transmitter and antenna - is swallowed with water after a 12 h fast. The capsule is propelled via peristalsis through the gastrointestinal tract and is excreted naturally. We will review all recent work concerning SBCE.
At present there are three other SBCEs in the market. SBCE has become a first-line tool to detect abnormalities in the small bowel, as all other imaging technologies are rather ineffective, or very tedious.Indications for SBCE include obscure gastrointestinal bleeding, suspected small bowel tumor, suspected Crohn's disease, surveillance of inherited polyposis syndromes, drug-induced small bowel injury or any abnormal small bowel imaging and new ones are emerging like small bowel motility. Since most of the articles in the literature relate to the PillCam small bowel capsule the data presented will refer mainly to this capsule endoscopy.
SBCE has shed new light into our knowledge of the small bowel, paving the way for new modalities to come.
自小肠胶囊内镜 (SBCE) 首次引入胃肠道领域以来,已经过去了 8 年多。最初的胶囊(以色列 YoKneam 的 Given Imaging 公司生产)为一次性使用的 26 x 11 毫米视频胶囊,内置光学穹顶、光源、电池、发射器和天线,在禁食 12 小时后用水冲服。胶囊通过蠕动推进胃肠道并自然排出。我们将对所有关于 SBCE 的最新研究进行综述。
目前市面上有另外三种 SBCE。由于其他所有成像技术的效果都不是很理想,或者非常繁琐,因此 SBCE 已成为检测小肠异常的一线工具。SBCE 的适应证包括不明原因的胃肠道出血、疑似小肠肿瘤、疑似克罗恩病、遗传性息肉综合征的监测、药物引起的小肠损伤或任何异常的小肠影像学表现,以及新出现的小肠动力障碍等。由于文献中的大多数文章都与 PillCam 小肠胶囊内镜有关,因此本文主要介绍这种胶囊内镜的数据。
SBCE 为我们对小肠的认识带来了新的曙光,为新的治疗方法铺平了道路。