Chen Albert P, Cunningham Charles H, Ozturk-Isik Esin, Xu Duan, Hurd Ralph E, Kelley Douglas A C, Pauly John M, Kurhanewicz John, Nelson Sarah J, Vigneron Daniel B
Department of Radiology, University of California at San Francisco, San Francisco, CA 94143, USA.
J Magn Reson Imaging. 2007 Jun;25(6):1288-92. doi: 10.1002/jmri.20916.
Prostate MR spectroscopic imaging (MRSI) at 3T may provide two-fold higher spatial resolution over 1.5T, but this can result in longer acquisition times to cover the entire gland using conventional phase-encoding. In this study, flyback echo-planar readout trajectories were incorporated into a Malcolm Levitt's composite-pulse decoupling sequence (MLEV)-point-resolved spectroscopy sequence (PRESS) to accelerate the acquisition of large array (16 x 16 x 8), high spatial (0.154 cm(3)) resolution MRSI data by eight-fold to just 8.5 minutes. Artifact free, high-quality MRSI data was obtained in nine prostate cancer patients. Easy data reconstruction and the robustness of the flyback echo-planar encoding make this technique particularly suitable for the clinical setting. The short acquisition time provided by this method reduces the 3T prostate MRI/MRSI exam time, allows longer repetition times, and/or allows the acquisition of additional MR acquisitions within the same exam.
3T场强下的前列腺磁共振波谱成像（MRSI）可能比1.5T场强提供高一倍的空间分辨率，但使用传统相位编码覆盖整个腺体可能会导致采集时间更长。在本研究中，将回波平面读出轨迹纳入马尔科姆·莱维特复合脉冲去耦序列（MLEV）-点分辨波谱序列（PRESS），以将大阵列（16×16×8）、高空间分辨率（0.154 cm³）的MRSI数据采集速度提高八倍，至仅8.5分钟。在9例前列腺癌患者中获得了无伪影的高质量MRSI数据。回波平面编码易于数据重建且稳健，使得该技术特别适用于临床环境。该方法提供的短采集时间减少了3T前列腺MRI/MRSI检查时间，允许更长的重复时间，和/或允许在同一检查中采集额外的MR图像。
