Chiari I型畸形患者的青年起病性半面痉挛
Young onset Hemifacial Spasm in patients with Chiari type I malformation.
作者信息
Felício Andre Carvalho, de Godeiro Clecio, Borges Vanderci, de Azevedo Silva Sonia Maria, Ferraz Henrique Ballalai
机构信息
Movement Disorders Unit, Department of Neurology, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, Brazil.
出版信息
Parkinsonism Relat Disord. 2008;14(1):66-8. doi: 10.1016/j.parkreldis.2007.04.002. Epub 2007 May 22.
Hemifacial spasm (HFS) resulting from Chiari type I malformation (CIM) is rare. We retrospectively evaluated five patients with CIM and HFS among a series of 103 subjects. The frequency of HFS associated to CIM was of 4.85%. The clinical profile did not differ from the classical primary cases except for young-onset development of facial spasms in patients with CIM. Three patients were treated with BTX-A injections with favorable outcome. Although rare HFS may be associated with CIM especially in young subjects with peculiar phenotypic characteristics (short neck). Moreover, BTX may be an alternative to posterior fossa decompression in selected cases.
由 Chiari I 型畸形（CIM）导致的半面痉挛（HFS）很罕见。我们在一系列 103 名受试者中对 5 例患有 CIM 和 HFS 的患者进行了回顾性评估。与 CIM 相关的 HFS 发生率为 4.85%。除了 CIM 患者面部痉挛起病年龄较轻外，其临床特征与典型的原发性病例并无差异。3 例患者接受了肉毒杆菌毒素 A（BTX-A）注射治疗，效果良好。虽然罕见，但 HFS 可能与 CIM 有关，尤其是在具有特殊表型特征（短颈）的年轻受试者中。此外，在某些选定病例中，BTX 可能是后颅窝减压术的一种替代方法。
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