Palynyczko Z, Milewski B
Mater Med Pol. 1975 Oct-Dec;7(4):327-33.
In 317 patients with diseases of the liver and bile tract the authors determined LP-X in the serum and the obtained results were compared with the morphological findings in liver tissue or intraoperative examination of the extrahepatic bile ducts. Int he same patients serum bilirubin, total cholesterol, alkaline phosphatase activity, gamma-glutamyltranspeptidase and leucylaminopeptidase activity were determined. In the light of these results the authors believe that detection of LP-X in the serum is a sensitive and specific method in the diagnosis of cholestasis and that it is of greater usefulness than determination of alkaline phosphatase activity. Determinations of other biochemical parameters is of small diagnostic importance in these cases.
作者对317例肝胆疾病患者测定了血清中的LP-X，并将所得结果与肝组织的形态学检查结果或肝外胆管的术中检查结果进行了比较。对这些患者还测定了血清胆红素、总胆固醇、碱性磷酸酶活性、γ-谷氨酰转肽酶和亮氨酰氨基肽酶活性。根据这些结果，作者认为血清中LP-X的检测是诊断胆汁淤积的一种敏感且特异的方法，并且它比碱性磷酸酶活性的测定更有用。在这些病例中，其他生化参数的测定诊断意义较小。
