Seppänen S, Niittynen L, Poussa T, Korpela R
Department of Applied Chemistry and Microbiology, Nutrition, University of Helsinki, Helsinki, Finland.
Eur J Clin Nutr. 2008 Jun;62(6):727-32. doi: 10.1038/sj.ejcn.1602787. Epub 2007 May 16.
To investigate whether removing lactose from milk delays bowel function in lactose-tolerant women. We also examined how well the participants' subjective evaluation of the stool consistency according to the Bristol Stool Form Scale correlated with values obtained by dry matter analysis and penetrometry.
A randomized double-blind cross-over trial. Thirty-three lactose-tolerant women consumed, in random order, 800 ml of lactose-free or ordinary milk per day for 2 weeks, with their main meal, but otherwise followed a lactose-free diet. The subjects estimated stool consistency according to the Bristol Stool Form Scale, registered stool frequency and gastrointestinal symptoms and collected stool samples.
The mean intake of lactose was 3.5 and 38.4 g/day during the lactose-free and the ordinary milk periods, respectively. There were no statistically significant differences between the lactose-free and the ordinary milk periods in stool frequency, gastrointestinal symptoms, stool hardness or faecal dry matter. Faecal pH was lower during the lactose-free milk period than in the ordinary milk period. The subjective estimation of stool hardness correlated well with the values obtained by dry matter analysis and penetrometry.
Lactose-free milk does not delay bowel function in lactose-tolerant women. The Bristol Stool Form Scale is a useful method of evaluating stool hardness.
研究去除牛奶中的乳糖是否会延缓乳糖耐受女性的肠道功能。我们还研究了参与者根据布里斯托大便分类法对大便稠度的主观评估与通过干物质分析和贯入度测定获得的值之间的相关性。
一项随机双盲交叉试验。33名乳糖耐受女性随机顺序每天随主餐饮用800毫升无乳糖牛奶或普通牛奶，持续2周，其他时间遵循无乳糖饮食。受试者根据布里斯托大便分类法估计大便稠度，记录大便频率和胃肠道症状，并采集粪便样本。
在无乳糖牛奶期和普通牛奶期，乳糖的平均摄入量分别为3.5克/天和38.4克/天。无乳糖牛奶期和普通牛奶期在大便频率、胃肠道症状、大便硬度或粪便干物质方面无统计学显著差异。无乳糖牛奶期的粪便pH值低于普通牛奶期。对大便硬度的主观评估与通过干物质分析和贯入度测定获得的值相关性良好。
无乳糖牛奶不会延缓乳糖耐受女性的肠道功能。布里斯托大便分类法是评估大便硬度的一种有用方法。
