Hosokawa Osamu, Hattori Masakazu, Douden Kenji, Hayashi Hiroyuki, Ohta Kouji, Kaizaki Yasuharu
Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan.
Hepatogastroenterology. 2007 Mar;54(74):442-4.
BACKGROUND/AIMS: There are few reports regarding the accuracy of endoscopy in detecting cancer. We investigated the difference in the false-negative rates for cancer detection between gastroscopy and colonoscopy using the records of a population-based cancer registry, which is the most accurate in Japan.
Between 1990 and 1995, 51,411 gastroscopic and 7756 colonoscopic examinations were carried out in our hospital. These subjects were matched with the cancer registry and the patients whose gastric or colorectal cancers were missed by examinations were identified.
The false-negative rate for the detection with gastroscopy was 25.8 percent at three years but that with colonoscopy was 11.1 percent. This difference was statically significant p = 0.01.
We concluded that for routine examinations, surveillance after negative endoscopy should be discussed based on the difference in false-negative rates between gastroscopy and colonoscopy.
背景/目的：关于内镜检查在癌症检测中的准确性的报道较少。我们利用日本最准确的基于人群的癌症登记记录，调查了胃镜检查和结肠镜检查在癌症检测中的假阴性率差异。
1990年至1995年期间，我院进行了51411例胃镜检查和7756例结肠镜检查。这些受试者与癌症登记记录进行匹配，并确定那些在检查中漏诊胃癌或结直肠癌的患者。
胃镜检查三年时的癌症检测假阴性率为25.8%，而结肠镜检查为11.1%。这种差异具有统计学意义（p = 0.01）。
我们得出结论，对于常规检查，应根据胃镜检查和结肠镜检查假阴性率的差异，讨论内镜检查阴性后的监测问题。
