Aksenova L Iu, Buravtseva N P, Kogotkova O I, Eremenko E I, Tsygankova O I
Zh Mikrobiol Epidemiol Immunobiol. 2007 Jan-Feb(1):34-7.
Study showed that cultural, morphologic, genetic, immunologic characteristics, and resistance to antibiotics of STI-PR anthrax vaccine did not change after storage during 20 years in lyophilized condition. It has been shown that medium for lyophilization plays important role in preservation of vitality of anthrax spores. Optimal preservative properties have been observed for thioureal and sucrose-gelatinous media for lyophilization. Obtained results give reasons for prolongation of shelf live of STI-PR vaccine from 2 - 3 to 5 - 8 years.
