[以冻干孢子形式保存30年的炭疽疫苗菌株STI-1的特性]

[Characteristics of the anthrax vaccinal strain STI-1 preserved for 30 years in the form of lyophilized spores].

作者信息

Saltykov R A, Bakulov I A, Gavrilov V A, Ulanova A A, Kivaev V A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1976 Jun(6):62-5.

Abstract

A study was made of the biological properties of the spore culture of anthrax vaccine strain STI-1 lyophilized in 1944 and kept for 30 years without any passages. This dry culture contained not less than 29% of live spores; the culture growth in the nutrient broth and on the agar medium was typical for the strain. Immunogenicity tested in experiments on guinea pigs and rabbits was not reduced and corresponded to that of the reference STI-1 vaccine.

摘要

对1944年冻干保存且30年未传代的炭疽疫苗株STI-1的芽孢培养物的生物学特性进行了研究。这种干燥培养物含有不少于29%的活芽孢；在营养肉汤和琼脂培养基上的培养生长是该菌株的典型特征。在豚鼠和兔子身上进行实验测试的免疫原性未降低，与参考STI-1疫苗相当。