[具有拮抗活性的屎肠球菌非致病菌株的筛选]
[Screening of nonpathogenic strains of Enterococcus faecium with antagonistic activity].
作者信息
Chervinets V M, Bondarenko V M, Samoukina A M, Chervinets Iu V
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 2007 Jan-Feb(1):57-61.
Forty two strains of enterococci were isolated from feces of healthy adolescents. Strains were selected according to their antagonistic effects associated with bacteriocinogenic and microcinogenic activity. Resistance of enterococci to antibiotics, various concentrations of hydrochloric acid and bile, their level of production of organic acids and adhesiveness were determined. Characteristics related to pathogenicity were investigared in 5 microcinogenic strains of E. faecium with broad spectrum of antagonistic activity. Non-pathogenic microcin-producing strains of E. faecium resistant to physiological concentrations of hydrochloric acid and bile with broad spectrum of antagonistic activity against obligatory pathogenic and opportunistic microorganisms can be considered as possessing probiotic activity.
从健康青少年粪便中分离出42株肠球菌。根据其与产细菌素和产微菌素活性相关的拮抗作用来选择菌株。测定了肠球菌对抗生素、不同浓度盐酸和胆汁的抗性、有机酸产生水平及黏附性。对5株具有广泛拮抗活性的产微菌素屎肠球菌菌株的致病性相关特征进行了研究。对生理浓度盐酸和胆汁具有抗性、对 obligatory pathogenic和机会性微生物具有广泛拮抗活性的非致病性产微菌素屎肠球菌菌株可被认为具有益生菌活性。 （注：“obligatory pathogenic”表述不太准确，可能存在错误，推测可能是“obligate pathogenic”即“专性致病的” ）
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