Kazimirova A A, Volosnikov D K, Bakhareva L I, Kandalova E N
Zh Mikrobiol Epidemiol Immunobiol. 2007 Mar-Apr(2):71-5.
Qualitative and quantitative composition of gastric microflora has been studied in 30 children with chronic gastritis. Bacteriological study of gastric biopsies and parietal mucus in 10 children with chronic gastritis not associated with Helicobacter pylori more frequently revealed conditionally pathogenic bacteria--Escherichia coli, Staphylococcus aureus, Streptococcus viridans, S. pyogenes (group A), Peptostreptococcus anaerobius, P. prevotii and their associations. In 20 studied patients with H.pylori-associated chronic gastritis composition of local microflora was less diverse--conditionally pathogenic, lacto- and bifidobacteria often were absent. Study showed that eradication of H. pylori led to appearance of conditionally pathogenic bacteria in stomach microflora, which were frequently isolated in associations. Not effective treatment was associated with disappearance of lacto- and bifidobacteria and frequent isolation of Candida albicans.
对30例慢性胃炎患儿的胃微生物群的定性和定量组成进行了研究。对10例与幽门螺杆菌无关的慢性胃炎患儿的胃活检组织和壁层黏液进行细菌学研究，更频繁地发现了条件致病菌——大肠杆菌、金黄色葡萄球菌、草绿色链球菌、化脓性链球菌（A组）、厌氧消化链球菌、普氏消化链球菌及其组合。在20例幽门螺杆菌相关性慢性胃炎患者中，局部微生物群的组成多样性较低——通常不存在条件致病菌、乳酸菌和双歧杆菌。研究表明，根除幽门螺杆菌会导致胃微生物群中出现条件致病菌，这些细菌经常以组合形式被分离出来。治疗无效与乳酸菌和双歧杆菌的消失以及白色念珠菌的频繁分离有关。
