Suppr超能文献

受监管注射设施使用者群体中戒毒服务的使用率及其影响。

Rate of detoxification service use and its impact among a cohort of supervised injecting facility users.

作者信息

Wood Evan, Tyndall Mark W, Zhang Ruth, Montaner Julio S G, Kerr Thomas

机构信息

British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital and Department of Medicine, University of British Columbia, Canada.

出版信息

Addiction. 2007 Jun;102(6):916-9. doi: 10.1111/j.1360-0443.2007.01818.x.

Abstract

BACKGROUND

Vancouver, Canada recently opened a medically supervised injecting facility (SIF) where injection drug users (IDU) can inject pre-obtained illicit drugs. Critics suggest that the facility does not help IDU to reduce their drug use.

METHODS

We conducted retrospective and prospective database linkages with residential detoxification facilities and used generalized estimating equation (GEE) methods to examine the rate of detoxification service use among SIF participants in the year before versus the year after the SIF opened. In secondary analyses, we used Cox regression to examine if having been enrolled in detoxification was associated with enrolling in methadone or other forms of addiction treatment. We also evaluated the impact of detoxification use on the frequency of SIF use.

RESULTS

Among 1031 IDU, there was a statistically significant increase in the uptake of detoxification services the year after the SIF opened. [odds ratio: 1.32 (95% CI, 1.11-1.58); P = 0.002]. In turn, detoxification was associated independently with elevated rates of methadone initiation [relative hazard = 1.56 (95% CI, 1.04-2.34); P = 0.031] and elevated initiation of other addiction treatment [relative hazard = 3.73 (95% CI, 2.57-5.39); P < 0.001]. Use of the SIF declined when the rate of SIF use in the month before enrolment into detoxification was compared to the rate of SIF use in the month after discharge (24 visits versus 19 visits; P = 0.002).

CONCLUSIONS

The SIF's opening was associated independently with a 30% increase in detoxification service use, and this behaviour was associated with increased rates of long-term addiction treatment initiation and reduced injecting at the SIF.

摘要

背景

加拿大温哥华最近开设了一家有医疗监督的注射设施(SIF),注射吸毒者(IDU)可以在该设施注射预先获取的非法药物。批评者认为该设施无助于注射吸毒者减少吸毒。

方法

我们对住院戒毒设施进行了回顾性和前瞻性数据库关联,并使用广义估计方程(GEE)方法来检查SIF开放前一年与开放后一年SIF参与者中戒毒服务的使用率。在二次分析中,我们使用Cox回归来检查参加戒毒是否与参加美沙酮或其他形式的成瘾治疗有关。我们还评估了戒毒服务的使用对SIF使用频率的影响。

结果

在1031名注射吸毒者中,SIF开放后一年戒毒服务的使用率有统计学意义的增加。[优势比:1.32(95%可信区间,1.11 - 1.58);P = 0.002]。反过来,戒毒独立地与美沙酮起始率升高[相对风险 = 1.56(95%可信区间,1.04 - 2.34);P = 0.031]和其他成瘾治疗起始率升高[相对风险 = 3.73(95%可信区间,2.57 - 5.39);P < 0.001]相关。将进入戒毒前一个月的SIF使用率与出院后一个月的SIF使用率进行比较时,SIF的使用量下降(24次就诊对19次就诊;P = 0.002)。

结论

SIF的开放独立地与戒毒服务使用率增加30%相关,并且这种行为与长期成瘾治疗起始率增加和SIF处注射减少相关。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验