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肝脏的“孤立性”坏死结节:病因再确认

'Solitary' necrotic nodules of the liver: an aetiology reaffirmed.

作者信息

Sundaresan M, Lyons B, Akosa A B

机构信息

Department of Histopathology, Hammersmith Hospital, London.

出版信息

Gut. 1991 Nov;32(11):1378-80. doi: 10.1136/gut.32.11.1378.

DOI:10.1136/gut.32.11.1378
PMID:1752472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1379172/
Abstract

Morphological features of lesions conforming to the description of solitary necrotic nodules of the liver were compared with liver haemangiomata and necrotic tumour metastases in the liver. An origin in haemangiomata is confirmed for most of the lesions studied, although the necrotic nodule may represent the end stage of a variety of lesions. These lesions are usually benign, although necrotic nodules are often mistaken for liver metastases. A reticulin stain is useful in assessing the lesions.

摘要

将符合肝脏孤立性坏死结节描述的病变形态学特征与肝脏海绵状血管瘤及肝脏坏死性肿瘤转移灶进行了比较。尽管坏死结节可能代表多种病变的终末期,但研究的大多数病变证实起源于海绵状血管瘤。这些病变通常为良性,不过坏死结节常被误诊为肝转移瘤。网状纤维染色有助于评估这些病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ed/1379172/fa62ca4aeaad/gut00592-0137-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ed/1379172/499e552d3318/gut00592-0137-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ed/1379172/bd854918042d/gut00592-0137-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ed/1379172/fa62ca4aeaad/gut00592-0137-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ed/1379172/499e552d3318/gut00592-0137-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ed/1379172/bd854918042d/gut00592-0137-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ed/1379172/fa62ca4aeaad/gut00592-0137-c.jpg

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本文引用的文献

1
Larval granulomata in the liver.肝脏中的幼虫肉芽肿。
Gut. 1962 Dec;3(4):289-94. doi: 10.1136/gut.3.4.289.
2
Solitary necrotic nodules of the liver simulating hepatic metastases.酷似肝转移瘤的肝脏孤立性坏死结节。
J Clin Pathol. 1983 Oct;36(10):1181-3. doi: 10.1136/jcp.36.10.1181.
3
Solitary "necrotic nodule" of the liver: a probable pathogenesis.肝脏孤立性“坏死结节”:一种可能的发病机制。
肝脏孤立性坏死结节伴“环状”钙化:病例报告
World J Clin Cases. 2022 Jul 26;10(21):7409-7414. doi: 10.12998/wjcc.v10.i21.7409.
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Focal solitary necrotic nodules in fatty liver: characteristics on conventional and contrast-enhanced ultrasonography.肝内局灶性单发坏死性结节:常规超声与超声造影特征。
J Ultrasound. 2022 Dec;25(4):847-854. doi: 10.1007/s40477-021-00634-3. Epub 2022 Jan 29.
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Enlarged solitary necrotic nodule of the liver misinterpreted as a metastatic liver cancer.肝脏孤立性坏死结节增大,被误诊为转移性肝癌。
Clin J Gastroenterol. 2009 Oct;2(5):355-360. doi: 10.1007/s12328-009-0103-y. Epub 2009 Sep 2.
6
A case of solitary necrotic nodule treated with laparoscopic hepatectomy: spontaneous regression of hepatocellular carcinoma?1例经腹腔镜肝切除术治疗的孤立性坏死结节:肝细胞癌自发消退?
Case Reports Hepatol. 2013;2013:723781. doi: 10.1155/2013/723781. Epub 2013 Mar 19.
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Solitary necrotic nodule of the liver: a very challenging diagnosis!肝脏孤立性坏死结节:极具挑战性的诊断!
BMJ Case Rep. 2014 Feb 27;2014:bcr2013202364. doi: 10.1136/bcr-2013-202364.
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Solitary necrotic nodule of the liver: radiologic-pathologic correlation in a case with unusual imaging features.肝脏孤立性坏死性结节:一例具有不同寻常影像学特征的病例的放射-病理相关性。
Jpn J Radiol. 2013 Apr;31(4):277-81. doi: 10.1007/s11604-012-0173-5. Epub 2012 Dec 26.
9
Solitary Necrotic Nodules of the Liver: Histology and Diagnosis With CT and MRI.肝脏孤立性坏死结节:组织学及CT与MRI诊断
Hepat Mon. 2012 Aug;12(8):e6212. doi: 10.5812/hepatmon.6212. Epub 2012 Aug 20.
10
Pinworm infection masquerading as colorectal liver metastasis.伪装成结直肠肝转移的蛲虫感染
Ann R Coll Surg Engl. 2012 Sep;94(6):e195-7. doi: 10.1308/003588412X13373405384891.
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Liver lesions in an autopsy population.尸检人群中的肝脏病变
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