Grazi G L, Mazziotti A, Gruttadauria S, Jovine E, Principe A, Cavallari A
Department of Surgery and Transplantation, University of Bologna, Sant' Orsola Hospital, Italy.
Am Surg. 1998 Aug;64(8):764-7.
An experience is reported with solitary necrotic nodules of the liver, rare benign lesions described for the first time in 1983. Two patients were referred to our department because of the presence of hepatic lesions that radiology showed to be suspected secondary liver tumors. At laparotomy, both patients underwent liver resections because the lesions appeared to be malignant. Subsequent histological examination of the surgical specimens revealed that both were solitary necrotic nodules of the liver. These were the only solitary necrotic nodules found in a total of 840 operations carried out in our department since October 1981. Although they are completely benign, solitary necrotic nodules have a similar ultrasound pattern and radiological features to metastases and have been described in the literature during the follow-up of patients with other tumors. Uncertainty remains as to the etiology of these lesions, which still represent an occasional finding in liver surgery.
本文报告了1例肝脏孤立性坏死结节的病例，该罕见良性病变于1983年首次被描述。两名患者因肝脏病变被转诊至我科，放射学检查显示怀疑为继发性肝肿瘤。在剖腹手术中，由于病变看起来像是恶性的，两名患者均接受了肝脏切除术。随后对手术标本进行的组织学检查显示，两者均为肝脏孤立性坏死结节。这是自1981年10月以来在我科进行的总共840例手术中仅发现的孤立性坏死结节。尽管它们完全是良性的，但孤立性坏死结节具有与转移瘤相似的超声图像和放射学特征，并且在文献中曾在其他肿瘤患者的随访过程中被描述过。这些病变的病因仍不确定，在肝脏手术中仍属偶然发现。
