Kang Seung-gu, Saven Jeffery G
Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104, USA.
Curr Opin Chem Biol. 2007 Jun;11(3):329-34. doi: 10.1016/j.cbpa.2007.05.006. Epub 2007 May 23.
Computational protein design has blossomed with the development of methods for addressing the complexities involved in specifying the structure, sequence and function of proteins. Recent applications include the design of novel functional membrane and soluble proteins, proteins incorporating non-biological components and protein combinatorial libraries.
随着用于解决蛋白质结构、序列和功能确定过程中所涉及复杂性的方法的发展，计算蛋白质设计蓬勃发展。近期的应用包括新型功能性膜蛋白和可溶性蛋白的设计、包含非生物成分的蛋白质设计以及蛋白质组合文库的设计。
