de Haseth Kristin, Cheung Ning, Saw Seang Mei, Islam F M Amirul, Mitchell Paul, Wong Tien Yin
Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.
Am J Ophthalmol. 2007 Jun;143(6):1040-2. doi: 10.1016/j.ajo.2007.01.032.
To determine whether intraocular pressure (IOP) influences retinal vascular caliber in young children, in order to provide a better understanding of its physiological determinants.
Cross-sectional study.
Three hundred and eighty-six Chinese children seven to nine years of age participated in the Singapore Cohort Study of the Risk factors for Myopia (SCORM). IOP was measured by noncontact tonometry. Retinal vascular calibers were measured from retinal photographs using a computer-based program following standardized protocols.
After adjusting for age, gender, body mass index, corneal thickness, spherical equivalent refraction, axial length, and birth weight, mean retinal arteriolar and venular caliber were similar across the distribution of IOP (arteriolar caliber of 155.2 microm, 155.6 microm, 153.8 microm, 154.2 microm, P value for trends, 0.45; and venular caliber of 225.7 microm, 220.6 microm, 224.5 microm, 222.7 microm, P value for trends, 0.53; comparing increasing quartiles of IOP).
Our study provides no evidence that IOP influences retinal vascular caliber in healthy young children.
确定眼压（IOP）是否会影响幼儿的视网膜血管管径，以便更好地了解其生理决定因素。
横断面研究。
386名7至9岁的中国儿童参与了新加坡近视危险因素队列研究（SCORM）。使用非接触眼压计测量眼压。按照标准化方案，通过基于计算机的程序从视网膜照片测量视网膜血管管径。
在调整年龄、性别、体重指数、角膜厚度、等效球镜度、眼轴长度和出生体重后，在眼压分布范围内，平均视网膜小动脉和小静脉管径相似（小动脉管径分别为155.2微米、155.6微米、153.8微米、154.2微米，趋势P值为0.45；小静脉管径分别为225.7微米、220.6微米、224.5微米、222.7微米，趋势P值为0.53；比较眼压升高的四分位数）。
我们的研究没有提供证据表明眼压会影响健康幼儿的视网膜血管管径。
