Noohi S, Khaghani-Zadeh M, Javadipour M, Assari S, Najafi M, Ebrahiminia M, Pourfarziani V
Nephrology/Urology Research Center (NURC), Baqiyatallah Medical Sciences University, Tehran, Iran.
Transplant Proc. 2007 May;39(4):1074-8. doi: 10.1016/j.transproceed.2007.04.002.
Psychiatric comorbidities have been reported to be associated with low quality of life, but less attention has been paid to their impact on other morbidity measures. The aim of this study was to investigate the correlation of anxiety and depression with marital relation, sexual function, and sleep quality in kidney transplant recipients.
In a cross-sectional study between 2005 and 2006, 88 kidney transplant recipients were divided into four groups according to their scores of anxiety and depression using Hospital Anxiety Depression Scale (HADS): group I(anx) (anxiety score <11; n=64); group II(anx) (anxiety score >or= 11; n=24); group I(dep) (depression score <11; n=68); and group II(dep) (depression score >or= 11; n=20). Morbidity measures including quality of life (Short Form-36), marital adjustment (Revised Dyadic Adjustment Scale), sexual relationship (Relationship and Sexuality Scale), and quality of sleep (Pittsburgh Sleep Quality Index) were separately compared between groups of anxious versus nonanxious and depressed versus nondepressed.
Group I(anx), compared with group II(anx), displayed a better state of mental health (48.80 +/- 7.14 vs. 44.45 +/- 7.80; P=.01), general health (49.36 +/- 12.77 vs. 42.91 +/- 16.67; P=.05), marital adjustment (55.13 +/- 8.01 vs. 48.35 +/- 16.62; P=.04), and lower sleep disturbance (1.36 +/- 0.62 vs. 1.66 +/- 0.63; P=.05). Group I(dep), compared with group II(dep), showed lower fatigue score (39.79 +/- 8.30 vs. 46.84 +/- 8.85; P=.002) and better sexual relationships (15.28 +/- 5.50 vs. 19.00 +/- 5.92; P=.03).
Screening for anxiety and depression in kidney transplant recipients is essential. Appropriate treatment of these prevalent psychiatric comorbidities may improve various aspects of patient well-being, including quality of life, sleep, marital relations, and sexual relationship.
据报道，精神疾病合并症与生活质量低下有关，但人们对其对其他发病率指标的影响关注较少。本研究的目的是调查肾移植受者焦虑和抑郁与婚姻关系、性功能及睡眠质量之间的相关性。
在2005年至2006年的一项横断面研究中，88名肾移植受者根据医院焦虑抑郁量表（HADS）的焦虑和抑郁得分被分为四组：第一组（焦虑组）（焦虑得分<11；n = 64）；第二组（焦虑组）（焦虑得分≥11；n = 24）；第一组（抑郁组）（抑郁得分<11；n = 68）；第二组（抑郁组）（抑郁得分≥11；n = 20）。分别比较焦虑组与非焦虑组、抑郁组与非抑郁组在包括生活质量（简明健康状况调查量表-36）、婚姻调适（修订的二元调适量表）、性关系（关系与性量表）及睡眠质量（匹兹堡睡眠质量指数）等发病率指标方面的差异。
与第二组（焦虑组）相比，第一组（焦虑组）心理健康状况更好（48.80±7.14对44.45±7.80；P = 0.01）、总体健康状况更好（49.36±12.77对42.91±16.67；P = 0.05）、婚姻调适更好（55.13±8.01对48.35±16.62；P = 0.04）且睡眠障碍更低（1.36±0.62对1.66±0.63；P = 0.05）。与第二组（抑郁组）相比，第一组（抑郁组）疲劳得分更低（39.79±8.30对46.84±8.85；P = 0.002）且性关系更好（15.28±5.50对19.00±5.92；P = 0.03）。
对肾移植受者进行焦虑和抑郁筛查至关重要。对这些常见的精神疾病合并症进行适当治疗可能会改善患者幸福的各个方面,包括生活质量、睡眠、婚姻关系及性关系。
