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癫痫患者术前语言和记忆功能评估中Wada测试的非侵入性替代方法。

Non-invasive alternatives to the Wada test in the presurgical evaluation of language and memory functions in epilepsy patients.

作者信息

Pelletier Isabelle, Sauerwein Hannelore C, Lepore Franco, Saint-Amour Dave, Lassonde Maryse

机构信息

Centre de recherche du Centre Hospitalier Universitaire Mère-Enfant (Sainte-Justine), Canada.

出版信息

Epileptic Disord. 2007 Jun;9(2):111-26. doi: 10.1684/epd.2007.0109.

DOI:10.1684/epd.2007.0109
PMID:17525019
Abstract

The cognitive outcome of the surgical removal of an epileptic focus depends on the assessment of the localisation and functional capacity of language and memory areas which need to be spared by the neurosurgeon. Traditionally, presurgical evaluation of epileptic patients has been achieved by means of the intracarotid amobarbital test assisted by neuropsychological measures. However, the advent of neuroimaging techniques has provided new ways of assessing these functions by means of non-invasive or minimally invasive methods, such as anatomical and functional magnetic resonance imaging, positron emission tomography, single-photon emission computed tomography, transcranial magnetic stimulation, functional transcranial Doppler monitoring, magnetoencephalography and near infrared spectroscopy. This paper aims at comparing and evaluating the traditional and recent preoperative approaches from a neuropsychological perspective.

摘要

手术切除癫痫病灶的认知结果取决于对语言和记忆区域定位及功能能力的评估,神经外科医生需要避免损伤这些区域。传统上,癫痫患者的术前评估是通过颈动脉注射异戊巴比妥试验并辅以神经心理学测量来完成的。然而,神经成像技术的出现提供了通过非侵入性或微创方法评估这些功能的新途径,如解剖和功能磁共振成像、正电子发射断层扫描、单光子发射计算机断层扫描、经颅磁刺激、功能性经颅多普勒监测、脑磁图和近红外光谱。本文旨在从神经心理学角度比较和评估传统及最新的术前评估方法。

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Epileptic Disord. 2007 Jun;9(2):111-26. doi: 10.1684/epd.2007.0109.
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