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[基于格鲁吉亚矿泉水的药用软膏在治疗广泛性牙周炎中的抗菌特性]

[Antibacterial nature of medicinal ointments, based on Georgian mineral waters in treatment of generalized periodontitis].

作者信息

Gasviani E N, Chikviladze D P, Iverieli M V, Iavich P A, Mikeladze M L

出版信息

Georgian Med News. 2007 Apr(145):39-42.

PMID:17525497
Abstract

The goal of the work was to determine antibacterial nature of the medicinal ointments (N1 - "Achtala"; N2 - "Sairme", N3 - "Tschaltubo", N4 "Amagleba") based on Georgian mineral waters and containing bio-active extracts. The goal of the work was to determine antibacterial nature of the medicinal ointments (N1 - "Achtala"; N2 - "Sairme", N3 - "Tschaltubo", N4 "Amagleba") based on Georgian mineral waters and containing bio-active extracts. The investigation was done in purpose to determine microbial structure of oral cavity of the 80 patients with chronic generalized periodontitis, as a result was confirmed, that microbial structure of these patients was rather heterogeneous and is presented by different aerobe, microaerophil and anaerobe microbial flora. The sensitivity, resistance, of isolated microorganisms, was studied to modern groups of antibiotics. Results of investigations are: high antibacterial activities of ointments, prepared on mineral waters of Georgia. So, it can be recommended for usage in treatment schedule for patients with chronic generalized periodontitis.

摘要

这项工作的目的是确定基于格鲁吉亚矿泉水并含有生物活性提取物的药用软膏(N1 - “阿奇塔拉”;N2 - “萨尔梅”;N3 - “恰尔图博”;N4 - “阿马格列巴”)的抗菌特性。这项工作的目的是确定基于格鲁吉亚矿泉水并含有生物活性提取物的药用软膏(N1 - “阿奇塔拉”;N2 - “萨尔梅”;N3 - “恰尔图博”;N4 - “阿马格列巴”)的抗菌特性。为确定80例慢性广泛性牙周炎患者口腔的微生物结构进行了调查,结果证实,这些患者的微生物结构相当异质,由不同的需氧菌、微需氧菌和厌氧菌微生物群组成。研究了分离出的微生物对现代抗生素组的敏感性和耐药性。研究结果如下:基于格鲁吉亚矿泉水制备的软膏具有很高的抗菌活性。因此,它可推荐用于慢性广泛性牙周炎患者的治疗方案。

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