Pras E, Steinlauf S, Sidi Y
Dept. of Medicine D, Beilinson Medical Center, Petah Tikva.
Harefuah. 1991 Nov 15;121(10):380-1.
2 cases of cholestatic hepatitis due to preajmaline recovered when the drug was stopped. One was a 40-year-old woman, and the other a 74-year-old man whose jaundice lasted for 8 months. Approximately 40 patients with preajmaline-induced hepatitis have been described in the literature. All recovered except 1, who developed biliary cirrhosis while using preajmaline in conjunction with other hepatotoxic drugs.
2例因使用丙吡胺导致的胆汁淤积性肝炎在停药后痊愈。1例为40岁女性,另1例为74岁男性,其黄疸持续了8个月。文献中已报道了约40例丙吡胺所致肝炎患者。除1例在使用丙吡胺同时联用其他肝毒性药物而发展为胆汁性肝硬化外,其余均已康复。