Karsidag S, Sahin S, Hacikerim Karsidag S, Ayalp S
Department of Neurology, Faculty of Medicine, Maltepe University, Istanbul, Turkey.
Eura Medicophys. 2007 Sep;43(3):327-32. Epub 2007 May 28.
Carpal tunnel syndrome (CTS) is one of the most common compression neuropathies in neurology. Electromyography (EMG) including nerve conduction study (NCS) is the most useful diagnostic technique for CTS. In this study, we aim to demonstrate changes in electrophysiological parameters in different level of CTS patients by frequent EMG studies.
We prospectively followed patients with CTS regularly once every 12 weeks for 1 year. Fourteen women (28 hands) with EMG/NCS findings of CTS were observed and classified in 3 groups according to electrophysiological severity. All patients were instructed to wear the splint for 12 weeks. At the end of this period, patients were evaluated by electrophysiologic parameters. If findings were still abnormal, they were encouraged to continue wearing the splint. In severe cases, surgical release was carried out.
No statistically significant changes were noted in EMG recordings of mild cases repeated every 3 months. It was determined that significant improvements begin to occur in the moderate group in all parameters, except for the amplitude of the median sensory nerve. However, when the mean values were studied in the severe CTS group, it was observed that the preoperative motor and sensory parameters became increasingly impaired, but approached the initial values in the first evaluation in the postoperative period.
Subjects with CTS, particularly moderate as determined by electrophysiology, may benefit from conservative therapy, with improvements which continue for about one year. In severe cases the main treatment modality seems to be operation. Frequent electrophysiological follow-ups may be useful in guiding treatment.
腕管综合征(CTS)是神经病学中最常见的压迫性神经病变之一。包括神经传导研究(NCS)在内的肌电图(EMG)是诊断CTS最有用的技术。在本研究中,我们旨在通过频繁的肌电图研究来证明不同程度CTS患者电生理参数的变化。
我们对CTS患者进行前瞻性研究,每12周定期随访一次,为期1年。观察14名女性(28只手),其肌电图/神经传导研究结果显示患有CTS,并根据电生理严重程度分为3组。所有患者均被要求佩戴夹板12周。在此期间结束时,通过电生理参数对患者进行评估。如果结果仍异常,则鼓励他们继续佩戴夹板。在严重病例中,进行手术松解。
轻度病例每3个月重复进行的肌电图记录中未发现统计学上的显著变化。确定中度组除正中感觉神经振幅外的所有参数均开始出现显著改善。然而,在重度CTS组研究平均值时,观察到术前运动和感觉参数逐渐受损,但在术后首次评估中接近初始值。
CTS患者,尤其是通过电生理学确定为中度的患者,可能从保守治疗中获益,改善可持续约一年。在严重病例中,主要治疗方式似乎是手术。频繁的电生理随访可能有助于指导治疗。